In this issue of Cell Chemical Biology, Telling et al. (2017) apply advanced X-ray microscopy techniques to reveal magnetite iron species in plaques from a mouse model of Alzheimer's disease. The characterization of abnormal iron chemistry in the disease model highlights the potential for iron to combine with the β-amyloid peptide and accelerate the disease process
Abnormal accumulation of brain metals is a key feature of Alzheimer’s disease (AD). Formation of amy...
Recent work has demonstrated increased levels of redox-active iron biominerals in Alzheimer’s diseas...
Over the decades, various studies have established an association between accumulation of iron and b...
A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aβ) fibrils i...
A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aβ) fibrils i...
A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aβ) fibrils i...
Iron (Fe) is an essential trace element required for healthy brain function. Yet, disrupted iron neu...
Although it has been known for over 50 years that abnormal concentrations of iron are associated wit...
Altered metabolism of biometals in the brain is a key feature of Alzheimer’s disease, and biometal i...
Iron (Fe) is an essential trace element required for healthy brain function. Yet, disrupted iron neu...
AbstractOne of the characteristics of many neurodegenerative diseases is the disruption of normal ir...
There is a well-established literature indicating a relationship between iron in brain tissue and Al...
There is a well-established literature indicating a relationship between iron in brain tissue and Al...
Copyright © 2014 The Authors. Published by the Royal Society under the terms of the Creative Commons...
Background: Chemical imaging of the human brain has great potential for diagnostic and monitoring pu...
Abnormal accumulation of brain metals is a key feature of Alzheimer’s disease (AD). Formation of amy...
Recent work has demonstrated increased levels of redox-active iron biominerals in Alzheimer’s diseas...
Over the decades, various studies have established an association between accumulation of iron and b...
A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aβ) fibrils i...
A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aβ) fibrils i...
A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aβ) fibrils i...
Iron (Fe) is an essential trace element required for healthy brain function. Yet, disrupted iron neu...
Although it has been known for over 50 years that abnormal concentrations of iron are associated wit...
Altered metabolism of biometals in the brain is a key feature of Alzheimer’s disease, and biometal i...
Iron (Fe) is an essential trace element required for healthy brain function. Yet, disrupted iron neu...
AbstractOne of the characteristics of many neurodegenerative diseases is the disruption of normal ir...
There is a well-established literature indicating a relationship between iron in brain tissue and Al...
There is a well-established literature indicating a relationship between iron in brain tissue and Al...
Copyright © 2014 The Authors. Published by the Royal Society under the terms of the Creative Commons...
Background: Chemical imaging of the human brain has great potential for diagnostic and monitoring pu...
Abnormal accumulation of brain metals is a key feature of Alzheimer’s disease (AD). Formation of amy...
Recent work has demonstrated increased levels of redox-active iron biominerals in Alzheimer’s diseas...
Over the decades, various studies have established an association between accumulation of iron and b...