LncRNAs have recently emerged as new and fundamental transcriptional and post-transcriptional regulators acting at multiple levels of gene expression. Indeed, lncRNAs participate in a wide variety of stem cell and developmental processes, acting in cis and/or in trans in the nuclear and/or in the cytoplasmic compartments, and generating an intricate network of interactions with RNAs, enhancers, and chromatin-modifier complexes. Given the versatility of these molecules to operate in different subcellular compartments, via different modes of action and with different target specificity, the interest in this research field is rapidly growing. Here, we review recent progress in defining the functional role of lncRNAs in stem cell biology with a...
Long non-coding RNAs (lncRNAs) are a novel class of gene regulators playing multifaceted roles in ph...
Mammalian genomes encode many thousands of long non-coding RNAs (lncRNAs) that play important roles ...
Most of RNA transcripts, instead of serving templates for protein synthesis, perform different funct...
LncRNAs have recently emerged as new and fundamental transcriptional and post-transcriptional regula...
Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells occupy a...
Long noncoding RNAs (lncRNAs) comprise a class of regulatory molecules that may control diverse stem...
International audienceThe transcription of essentially the entire eukaryotic genome generates a myri...
In recent years, long noncoding RNAs (lncRNAs) have emerged as an important class of regulators of g...
SummaryHematopoietic stem cells (HSCs) possess unique gene expression programs that enforce their id...
Transcriptomic studies have demonstrated that the vast majority of the genomes of mammals and other ...
It is now clear that eukaryotic cells produce many thousands of non-coding RNAs. The least well-stud...
Genomes of multicellular organisms are characterized by the pervasive expression of different types ...
Embryonic stem cells (ESCs) hold great promises for treating and studying numerous devastating disea...
Two decades ago, the existence of long non-coding RNAs (lncRNAs) was discovered. In the following ge...
Given the self-renewal, multi-differentiation, immunoregulatory, and tissue maintenance properties, ...
Long non-coding RNAs (lncRNAs) are a novel class of gene regulators playing multifaceted roles in ph...
Mammalian genomes encode many thousands of long non-coding RNAs (lncRNAs) that play important roles ...
Most of RNA transcripts, instead of serving templates for protein synthesis, perform different funct...
LncRNAs have recently emerged as new and fundamental transcriptional and post-transcriptional regula...
Noncoding RNAs are critical regulatory factors in essentially all forms of life. Stem cells occupy a...
Long noncoding RNAs (lncRNAs) comprise a class of regulatory molecules that may control diverse stem...
International audienceThe transcription of essentially the entire eukaryotic genome generates a myri...
In recent years, long noncoding RNAs (lncRNAs) have emerged as an important class of regulators of g...
SummaryHematopoietic stem cells (HSCs) possess unique gene expression programs that enforce their id...
Transcriptomic studies have demonstrated that the vast majority of the genomes of mammals and other ...
It is now clear that eukaryotic cells produce many thousands of non-coding RNAs. The least well-stud...
Genomes of multicellular organisms are characterized by the pervasive expression of different types ...
Embryonic stem cells (ESCs) hold great promises for treating and studying numerous devastating disea...
Two decades ago, the existence of long non-coding RNAs (lncRNAs) was discovered. In the following ge...
Given the self-renewal, multi-differentiation, immunoregulatory, and tissue maintenance properties, ...
Long non-coding RNAs (lncRNAs) are a novel class of gene regulators playing multifaceted roles in ph...
Mammalian genomes encode many thousands of long non-coding RNAs (lncRNAs) that play important roles ...
Most of RNA transcripts, instead of serving templates for protein synthesis, perform different funct...