Identification of the virulence gene of Mycobacterium tuberculosis

Includes bibliographical references (leaves [103]-119).The major thrust of this project is to identify and characterize potential virulence genes from M. tuberculosis. To this end, we have compiled and integrated information from various public databases to catalogue 246573 microbial genes from 84 organisms, including pathogens and non pathogenic microbes. We determined the phylogenetic distributions by grouping the proteins into families based on sequence similarity with the aid of BLASTP and the NCBI BLASTClust program