The relationship of glycolytic/gluconeogenic intermediates in brewing yeast (Saccharomyces uvarum) fermentations to growth

Bibliography: pages 215-264.The objective of this study has been to understand the metabolic interrelationship between yeast growth, regulation of glycolytic/gluconeogenic flux and accumulation of glycosyl donors for polysaccharide synthesis in brewing yeast (Saccharomyces uvarum) fermentations. Loss of fermenting power of a brewing yeast population may be created by a condition that inhibits growth by limiting amino acid formation and protein synthesis. In commercial strains of S. uvarum this loss may be transitory, or, if not corrected, may ultimately lead to yeast degeneration. The potential industrial impact is realised for fermentation systems which may limit yeast growth, eg. continuous systems, use of pressure and, particularly, systems utilizing immobilised cells