Dihydroxynortropane alkaloids from calystegine-producing plants

Three dihydroxynortropanes, 2α,7β-dihydroxynortropane, 2α,3β-dihydroxynortropane, and 3α,7β-dihydroxynortropane, were isolated from calystegine-producing plants in the families Convolvulaceae and Solanaceae. 2α,7β-Dihydroxynortropane was isolated from six species in the Convolvulaceae whereas only Calystegia soldanella contained it and 2α,3β-dihydroxynortropane. Although neither of these were detectable in three species tested in the Solanaceae, 3α,7β-dihydroxynortropane was, however, isolated from Duboisia leichhardtii