Objective The composition of the healthy human adult gut microbiome is relatively stable over prolonged periods, and representatives of the most highly abundant and prevalent species have been cultured and described. However, microbial abundances can change on perturbations, such as antibiotics intake, enabling the identification and characterisation of otherwise low abundant species. Design Analysing gut microbial time-series data, we used shotgun metagenomics to create strain level taxonomic and functional profiles. Community dynamics were modelled postintervention with a focus on conditionally rare taxa and previously unknown bacteria. Results In response to a commonly prescribed cephalosporin (ceftriaxone), we observe a strong com...
<div><p>From birth onwards, the human gut microbiota rapidly increases in diversity and reaches an a...
<div><p>Next-generation sequencing has greatly contributed to an improved ecological understanding o...
The genus Lactobacillus includes over 215 species that colonize plants, foods, sewage and the gastro...
OBJECTIVE: The composition of the healthy human adult gut microbiome is relatively stable over prolo...
Introduction: Antimicrobial drugs are known to have effects on the human gut microbiota. We studied...
Advances in culture-independent research techniques have led to an increased understanding of the gu...
Each human body plays host to a microbial population which is both numerically vast (at around 1014 ...
Gut microbial communities can respond to antibiotic perturbations by rapidly altering their taxonomi...
Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here ...
© 2008 Author et al. This is an open-access article distributed under the terms of the Creative Comm...
Next-generation sequencing has greatly contributed to an improved ecological understanding of the hu...
Live bacteria (such as probiotics) have long been used to modulate gut microbiota and human physiolo...
<div><p>The human gut harbors thousands of bacterial taxa. A profusion of metagenomic sequence data ...
The microbiota, a community of micro-organisms in a particular environment, have been intensely rese...
Doctor of PhilosophyGenetics Interdepartmental ProgramMajor Professor Not ListedFundamental knowledg...
<div><p>From birth onwards, the human gut microbiota rapidly increases in diversity and reaches an a...
<div><p>Next-generation sequencing has greatly contributed to an improved ecological understanding o...
The genus Lactobacillus includes over 215 species that colonize plants, foods, sewage and the gastro...
OBJECTIVE: The composition of the healthy human adult gut microbiome is relatively stable over prolo...
Introduction: Antimicrobial drugs are known to have effects on the human gut microbiota. We studied...
Advances in culture-independent research techniques have led to an increased understanding of the gu...
Each human body plays host to a microbial population which is both numerically vast (at around 1014 ...
Gut microbial communities can respond to antibiotic perturbations by rapidly altering their taxonomi...
Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here ...
© 2008 Author et al. This is an open-access article distributed under the terms of the Creative Comm...
Next-generation sequencing has greatly contributed to an improved ecological understanding of the hu...
Live bacteria (such as probiotics) have long been used to modulate gut microbiota and human physiolo...
<div><p>The human gut harbors thousands of bacterial taxa. A profusion of metagenomic sequence data ...
The microbiota, a community of micro-organisms in a particular environment, have been intensely rese...
Doctor of PhilosophyGenetics Interdepartmental ProgramMajor Professor Not ListedFundamental knowledg...
<div><p>From birth onwards, the human gut microbiota rapidly increases in diversity and reaches an a...
<div><p>Next-generation sequencing has greatly contributed to an improved ecological understanding o...
The genus Lactobacillus includes over 215 species that colonize plants, foods, sewage and the gastro...