Add to ORKGThe increasing number of papers in which bioconjugates of oligo- and/or polypeptides are present indicates the importance and potential of these constructs. In this contribution there is an attempt to provide an overview of our results concerning the preparation, functional characterization and mainly biomedicinal application of conjugates with chemotherapeutic agents against tumour, infectious diseases, with T-cell epitope peptides or with “reporter” entities to be used also for mechanistic studies prepared in our laboratories last decades
Cell-penetrating peptides might have great potential for enhancing the therapeutic effect of drug mo...
In recent decades, the spectrum of available therapeutics has been expanded by the ever-growing fiel...
Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de F...
Drug conjugates have become a significant focus of research in the field of targeted medicine for ca...
Drug conjugates have become a significant focus of research in the field of targeted medicine for ca...
Thesis: Ph. D. in Biological Chemistry, Massachusetts Institute of Technology, Department of Chemist...
Development of peptide-based conjugates for targeted tumour therapy is a current research topic prov...
Infectious diseases caused by microbial pathogens (bacteria, virus, fungi, parasites) claim millions...
Cancer is the second leading cause of death affecting nearly one in two people, and the appearance o...
Peptide-drug conjugates (PDCs) have emerging applications in the safer delivery of chemotherapeutics...
The rich chemical and structural versatility of transition metal complexes provide numerous novel pa...
In recent decades, the spectrum of available therapeutics has been expanded by the ever-growing fiel...
A continuing problem in the area of oligonucleotide-based therapeutics is the poor access of these m...
We review drug conjugates combining a tumor-selective moiety with a cytotoxic agent as cancer treatm...
A continuing problem in the area of oligonucleotide-based therapeutics is the poor access of these m...
Cell-penetrating peptides might have great potential for enhancing the therapeutic effect of drug mo...
In recent decades, the spectrum of available therapeutics has been expanded by the ever-growing fiel...
Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de F...
Drug conjugates have become a significant focus of research in the field of targeted medicine for ca...
Drug conjugates have become a significant focus of research in the field of targeted medicine for ca...
Thesis: Ph. D. in Biological Chemistry, Massachusetts Institute of Technology, Department of Chemist...
Development of peptide-based conjugates for targeted tumour therapy is a current research topic prov...
Infectious diseases caused by microbial pathogens (bacteria, virus, fungi, parasites) claim millions...
Cancer is the second leading cause of death affecting nearly one in two people, and the appearance o...
Peptide-drug conjugates (PDCs) have emerging applications in the safer delivery of chemotherapeutics...
The rich chemical and structural versatility of transition metal complexes provide numerous novel pa...
In recent decades, the spectrum of available therapeutics has been expanded by the ever-growing fiel...
A continuing problem in the area of oligonucleotide-based therapeutics is the poor access of these m...
We review drug conjugates combining a tumor-selective moiety with a cytotoxic agent as cancer treatm...
A continuing problem in the area of oligonucleotide-based therapeutics is the poor access of these m...
Cell-penetrating peptides might have great potential for enhancing the therapeutic effect of drug mo...
In recent decades, the spectrum of available therapeutics has been expanded by the ever-growing fiel...
Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de F...