The pool of mature T cells comprises a heterogeneous mixture of naive and memory CD4(+) and CD8(+) cells. These cells are long lived at a population level but differ markedly in their relative rates of turnover and survival. Here, we review how contact with exogenous stimuli, notably self MHC ligands and various gamma(c) cytokines, plays a decisive role in controlling normal T cell homeostasis
<div><p>The processes regulating peripheral naive T-cell numbers and clonal diversity remain poorly ...
Post-thymic naïve T cells constitute a key cellular arm of adaptive immunity, with a well-known char...
Interactions between the T cell receptor (TCR) and major histocompatibility complex antigens are ess...
The immune system relies on homeostatic mechanisms in order to adapt to the changing requirements en...
The immune system relies on homeostatic mechanisms in order to adapt to the changing requirements en...
The peripheral mature T cell pool is regulated by complex homeostatic mechanisms. Naive T cells are ...
Weak T cell antigen receptor (TCR) signals from contact with self ligands act in synergy with antiap...
A system under homeostatic control tends to maintain its structure and functions by establishing dyn...
A system under homeostatic control tends to maintain its structure and functions by establishing dyn...
T cell homeostasis commonly refers to the maintenance of relatively stable T cell numbers in the per...
Homeostasis of T cells can be defined as the ability of the immune system to maintain normal T-cell ...
T cell homeostasis must be tightly controlled. In this issue of Immunity, Cho et al. (2010) describe...
AbstractPositive selection to self-MHC/peptide complexes has long been viewed as a device for skewin...
AbstractPeripheral T cell maintenance requires a survival signal delivered upon T cell receptor (TCR...
The processes regulating peripheral naive T-cell numbers and clonal diversity remain poorly understo...
<div><p>The processes regulating peripheral naive T-cell numbers and clonal diversity remain poorly ...
Post-thymic naïve T cells constitute a key cellular arm of adaptive immunity, with a well-known char...
Interactions between the T cell receptor (TCR) and major histocompatibility complex antigens are ess...
The immune system relies on homeostatic mechanisms in order to adapt to the changing requirements en...
The immune system relies on homeostatic mechanisms in order to adapt to the changing requirements en...
The peripheral mature T cell pool is regulated by complex homeostatic mechanisms. Naive T cells are ...
Weak T cell antigen receptor (TCR) signals from contact with self ligands act in synergy with antiap...
A system under homeostatic control tends to maintain its structure and functions by establishing dyn...
A system under homeostatic control tends to maintain its structure and functions by establishing dyn...
T cell homeostasis commonly refers to the maintenance of relatively stable T cell numbers in the per...
Homeostasis of T cells can be defined as the ability of the immune system to maintain normal T-cell ...
T cell homeostasis must be tightly controlled. In this issue of Immunity, Cho et al. (2010) describe...
AbstractPositive selection to self-MHC/peptide complexes has long been viewed as a device for skewin...
AbstractPeripheral T cell maintenance requires a survival signal delivered upon T cell receptor (TCR...
The processes regulating peripheral naive T-cell numbers and clonal diversity remain poorly understo...
<div><p>The processes regulating peripheral naive T-cell numbers and clonal diversity remain poorly ...
Post-thymic naïve T cells constitute a key cellular arm of adaptive immunity, with a well-known char...
Interactions between the T cell receptor (TCR) and major histocompatibility complex antigens are ess...
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