EFFICACY OF THREE ANTICOAGULANT RODENTICIDES FOR THE CONTROL OF POISON-SHY \u3ci\u3eRattus rattus\u3c/i\u3e

House rats (Rattus rattus) which do not consume a lethal dose of zinc phosphide develop poison-shyness after a single exposure. The surviving poison-shy rats cannot be baited again with zinc phosphide for about three months. Poison-shy rats were separately given anticoagulant baits (brodifa-coum 0.005%, coumatetralyl and warfarin 0.025%) in no-choice tests. The first two anticoagulants were found to be the most efficient ones. It was observed that those R. rattus which had consumed 56.7 mg/kg or more zinc phosphide died sooner (P \u3c 0.05 to 0.1) after anticoagulant poisoning when compared with normal rats. It is conjectured that prothrombin inhibition is accelerated in the liver of poison-shy R. rattus due to the action of phosphine present in the earlier ingested sublethal dose of zinc phosphide