Molecular mimicry of viral antigens with self determinants has been proposed as one of the pathogenic mechanisms in autoimmune disease. Evidence of viral mimicry in animal models of autoimmunity is accumulating. Murine adenovirus, Semliki forest virus, lactate dehydrogenase-elevating virus, herpes simplex virus type-1, hepatitis B virus, encephalomyocarditis virus, Theiler’s murine encephalomyelitis virus, Coxsackievirus and cytomegalovirus have been found to mimic physiologically important host proteins. However, epitope homology of a viral and self determinant is not in itself strong evidence for mimicry as a pathogenic mechanism. The mimicking determinant must also be capable of inducing disease in the absence of replicative virus. Anima...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
Viruses are suspected but usually unproven triggering factors in autoimmunity. One favored mechanism...
The paradigm for pathogenic autoimmunity is the generation of high-titre, affinity-matured autoantib...
The hypothesis that cross-reactivity between microbial and self determinants recognized by the adapt...
AbstractThe clinical association between viral infection and onset or exacerbation of autoimmune dis...
Mimicry of host antigens by infectious agents may induce cross-reactive autoimmune responses to epit...
The notion that mimicry between a self and a microbial peptide antigen can trigger or aggravate auto...
Two main etiological components are considered important in human autoimmune diseases including mult...
Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents may induce...
Abstract: The autoimmune diseases result from inappropriate responses of the immune system to self a...
Bacterial molecular mimicry in autoimmune diseases is one of the leading mechanisms by which microor...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
For more than three decades, molecular mimicry has been considered a contributing factor in viral pa...
Viruses share antigenic sites with normal host cell components, a phenomenon known as molecular mimi...
We have investigated two models of virally-induced autoimmune myocarditis in mice using widely diffe...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
Viruses are suspected but usually unproven triggering factors in autoimmunity. One favored mechanism...
The paradigm for pathogenic autoimmunity is the generation of high-titre, affinity-matured autoantib...
The hypothesis that cross-reactivity between microbial and self determinants recognized by the adapt...
AbstractThe clinical association between viral infection and onset or exacerbation of autoimmune dis...
Mimicry of host antigens by infectious agents may induce cross-reactive autoimmune responses to epit...
The notion that mimicry between a self and a microbial peptide antigen can trigger or aggravate auto...
Two main etiological components are considered important in human autoimmune diseases including mult...
Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents may induce...
Abstract: The autoimmune diseases result from inappropriate responses of the immune system to self a...
Bacterial molecular mimicry in autoimmune diseases is one of the leading mechanisms by which microor...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
For more than three decades, molecular mimicry has been considered a contributing factor in viral pa...
Viruses share antigenic sites with normal host cell components, a phenomenon known as molecular mimi...
We have investigated two models of virally-induced autoimmune myocarditis in mice using widely diffe...
Viral infections are involved in the pathogenesis of blood autoimmune diseases such as hemolytic ane...
Viruses are suspected but usually unproven triggering factors in autoimmunity. One favored mechanism...
The paradigm for pathogenic autoimmunity is the generation of high-titre, affinity-matured autoantib...