C-H functionalization reactions involve the activation of otherwise unreactive C-H bonds, and represent atom economical methods for the direct transformation of simple substrates to complex molecules. While transition metal-catalyzed C(sp²)-H functionalization reactions are regularly used in synthesis, C(sp³)-H functionalization is rarely applied to the synthesis of complex natural products because of the difficulties associated with controlling selectivity. With this in mind, we focused on the development of new palladium (Pd)(0)-catalyzed C(sp³)-H functionalization reactions for the synthesis of complex molecules, resulting in several new methods capable of solving these problems. We initially developed a concise synthetic method for the ...
The ability to selectively functionalize complex molecules is an ongoing challenge to chemists; the ...
Due to the ubiquity of heterocyclic scaffolds in naturally occurring compounds and pharmaceutical dr...
The ability to selectively functionalize complex molecules is an ongoing challenge to chemists; the ...
Heterocyclic compounds are commonly found in the core structures of several pharmaceuticals, natural...
Transition-metal-catalysed C–H bond functionalisation has exponentially developed as an efficient st...
xxiii, 512 pages : illustrations ; 30 cmPolyU Library Call No.: [THS] LG51 .H577P ABCT 2014 ChoyFunc...
Palladium-catalyzed processes provide an efficient strategy for functionalization of arenes and hete...
Palladium-catalyzed functionalization of C–H bonds is becoming an important synthetic tool that allo...
Over the past decades, the transition metal-catalysed intramolecular activation of unactivated C-H b...
Chapter 1 is a brief literature review of the most recent progress in the area of C-H functionalizat...
The Lautens group has a long-standing interest in developing novel approaches to heterocycle synthes...
The Lautens group has a long-standing interest in developing novel approaches to heterocycle synthes...
Chapter 1 is a brief review on some of the recents developments in palladium-catalysed C-H functiona...
Due to the ubiquity of heterocyclic scaffolds in naturally occurring compounds and pharmaceutical dr...
Our group has developed a strategy for the synthesis of benzofused carbocycles and heterocycles thro...
The ability to selectively functionalize complex molecules is an ongoing challenge to chemists; the ...
Due to the ubiquity of heterocyclic scaffolds in naturally occurring compounds and pharmaceutical dr...
The ability to selectively functionalize complex molecules is an ongoing challenge to chemists; the ...
Heterocyclic compounds are commonly found in the core structures of several pharmaceuticals, natural...
Transition-metal-catalysed C–H bond functionalisation has exponentially developed as an efficient st...
xxiii, 512 pages : illustrations ; 30 cmPolyU Library Call No.: [THS] LG51 .H577P ABCT 2014 ChoyFunc...
Palladium-catalyzed processes provide an efficient strategy for functionalization of arenes and hete...
Palladium-catalyzed functionalization of C–H bonds is becoming an important synthetic tool that allo...
Over the past decades, the transition metal-catalysed intramolecular activation of unactivated C-H b...
Chapter 1 is a brief literature review of the most recent progress in the area of C-H functionalizat...
The Lautens group has a long-standing interest in developing novel approaches to heterocycle synthes...
The Lautens group has a long-standing interest in developing novel approaches to heterocycle synthes...
Chapter 1 is a brief review on some of the recents developments in palladium-catalysed C-H functiona...
Due to the ubiquity of heterocyclic scaffolds in naturally occurring compounds and pharmaceutical dr...
Our group has developed a strategy for the synthesis of benzofused carbocycles and heterocycles thro...
The ability to selectively functionalize complex molecules is an ongoing challenge to chemists; the ...
Due to the ubiquity of heterocyclic scaffolds in naturally occurring compounds and pharmaceutical dr...
The ability to selectively functionalize complex molecules is an ongoing challenge to chemists; the ...