Increasing evidence suggests that lycopene, the major carotenoid present in tomato, may be preventive against smoke-induced cell damage. However, the mechanisms of such a prevention are still unclear. The aim of this study was to investigate the role of lycopene on the production of the pro-inflammatory cytokine IL-8 induced by cigarette smoke and the possible mechanisms implicated. Therefore, human THP-1 macrophages were exposed to cigarette smoke extract (CSE), alone and following a 6-h pre-treatment with lycopene (0.5-2 µM). CSE enhanced IL-8 production in a time- and a dose-dependent manner. Lycopene pre-treatment resulted in a significant inhibition of CSE-induced IL-8 expression at both mRNA and protein levels. NF-kB controlled the tr...
There is a lot of interest in the health benefits of dietary carotenoids and on the relationship of ...
Much of the beneficial effects of tomato lycopene in the prevention of chronic diseases has been att...
The present study was undertaken to examine whether lycopene is able to counteract 7-ketocholesterol...
Increasing evidence suggests that lycopene, the major carotenoid present in tomato, may be preventiv...
Increasing evidence suggests that lycopene, the major carotenoid present in tomato, may be preventiv...
Increasing evidence suggests that lycopene, the major carotenoid present in tomato, may be preventi...
Increasing evidence indicates that tomato lycopene may be an ideal candidate in protecting from canc...
Increasing evidence indicates that tomato lycopene may be an ideal candidate in protecting from canc...
<p>Panel A: IL-8 levels by reverse transcription polymerase chain reaction in cells treated for 6 h ...
Matrix metalloproteinase-9 (MMP-9) is a neutral proteinase involved in the breakdown and remodelling...
Matrix metalloproteinase-9 (MMP-9) is a neutral proteinase involved in the breakdown and remodellin...
There is a lot of interest in the health benefits of dietary carotenoids and on the relationship of ...
Matrix metalloproteinase-9 (MMP-9) has been implicated in both inflammation and fibrosis. It has bee...
Lycopene has antioxidant, anticancer, and anti-inflammatory effects with molecular mechanisms not fu...
There is a lot of interest in the health benefits of dietary carotenoids and on the relationship of ...
There is a lot of interest in the health benefits of dietary carotenoids and on the relationship of ...
Much of the beneficial effects of tomato lycopene in the prevention of chronic diseases has been att...
The present study was undertaken to examine whether lycopene is able to counteract 7-ketocholesterol...
Increasing evidence suggests that lycopene, the major carotenoid present in tomato, may be preventiv...
Increasing evidence suggests that lycopene, the major carotenoid present in tomato, may be preventiv...
Increasing evidence suggests that lycopene, the major carotenoid present in tomato, may be preventi...
Increasing evidence indicates that tomato lycopene may be an ideal candidate in protecting from canc...
Increasing evidence indicates that tomato lycopene may be an ideal candidate in protecting from canc...
<p>Panel A: IL-8 levels by reverse transcription polymerase chain reaction in cells treated for 6 h ...
Matrix metalloproteinase-9 (MMP-9) is a neutral proteinase involved in the breakdown and remodelling...
Matrix metalloproteinase-9 (MMP-9) is a neutral proteinase involved in the breakdown and remodellin...
There is a lot of interest in the health benefits of dietary carotenoids and on the relationship of ...
Matrix metalloproteinase-9 (MMP-9) has been implicated in both inflammation and fibrosis. It has bee...
Lycopene has antioxidant, anticancer, and anti-inflammatory effects with molecular mechanisms not fu...
There is a lot of interest in the health benefits of dietary carotenoids and on the relationship of ...
There is a lot of interest in the health benefits of dietary carotenoids and on the relationship of ...
Much of the beneficial effects of tomato lycopene in the prevention of chronic diseases has been att...
The present study was undertaken to examine whether lycopene is able to counteract 7-ketocholesterol...