Relationship between cardiac autonomic function and sustained ventricular tachyarrhythmias in patients with an implantable cardioverter defibrillators
- Barone, Lucy
- Mariani, Luca
- Infusino, Fabio
- Remoli, Romolo
- Careri, Giulia
- Pinnacchio, Gaetano
- Tarzia, Pierpaolo
- Lanza, Gaetano Antonio (ORCID:0000-0003-2187-6653)
- Crea, Filippo (ORCID:0000-0001-9404-8846)
- Battipaglia , Irma
DOIAbstract
AIMS: Low left ventricular ejection fraction (LVEF) is the main indication of implantable cardioverter defibrillators (ICD) in patients with dilated cardiomyopathy (DCM) for the primary prevention of sudden cardiac death, but ICD therapy at follow-up occurs in a minority of patients. We investigated whether heart rate variability (HRV) may improve risk stratification in DCM patients. METHODS AND RESULTS: We studied 42 patients (age 67.3 ± 3.5; 37 males) who had undergone ICD implant for either idiopathic or ischaemic DCM (LVEF <40%) 34.6 ± 19.7 months prior to the study (range 6-84). Patients underwent 24 h electrocardiographic Holter monitoring, and HRV was assessed over 2 hours in the afternoon showing stable sinus rhythm. Left ventric...
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