Is there significant improvement in neonatal outcome after treating pPROM mothers with amnio-infusion?

De Carolis, Maria Pia (ORCID:0000-0003-2054-8228)
Romagnoli, Costantino (ORCID:0000-0003-1176-2943)
De Santis, Marco (ORCID:0000-0002-1388-0014)
Piersigilli, F
Vento, Giovanni (ORCID:0000-0002-8132-5127)
Caruso, Alessandro (ORCID:0000-0002-4749-3207)

Open link

Publication date

January 2004

DOI

10.1159/000079657

Publisher

country:CHE

ISSN

1661-7800

Citation count (estimate)

Abstract

The aim of this study was to determine the effects of amnio-infusion treatment on fetal and neonatal mortality and neonatal pulmonary development in women with singleton pregnancies and premature rupture of the membranes occurring at a gestational age of <26 weeks and who had severe oligohydramnios. The treated group of 45 consenting women received serial amnio-infusion and was compared with the control group of 44 women who underwent waiting treatment. Our study confirmed a higher number of live births in the treated group, especially in cases with a gestational age at rupture (GAR) of <20 weeks. Furthermore, even if GAR is an important factor for predicting pulmonary hypoplasia, amnio-infusion treatment reduces the probability of pulmonar...