Add to ORKGBackground: Renal function is an important prescribing consideration. On average, glomerular filtration rate declines by about 10 mL/min every 10 years after the age of 40. Renal impairment may cause medicines to accumulate or cause toxicity, especially if the medicine has a narrow therapeutic index. Objective: To present an overview of prescribing considerations in the primary care setting for patients with chronic renal impairment. Discussion: Serum creatinine considered in isolation is not a reliable indicator of renal function. The estimated glomerular filtration rate provided in pathology reporting can alert prescribers to possible renal impairment and the need to consider dose adjustments. The Cockcroft-Gault equation should be used t...
The Modification of Diet in Renal Disease (MDRD) formula is widely used in clinical practice to asse...
ObjectivesTo determine how many ambulatory older adults with chronic kidney disease receive medicati...
Aging with multimorbidity and polytherapy are the most significant factors that could led to inappro...
ABSTRACT: BACKGROUND: Renal function decreases with age. Dosage adjustment according to renal functi...
BACKGROUND: Kidney function reduces with age, increasing the risk of harm from increased blood level...
The aging process is characterized by relevant changes in pharmacokinetics. Renal function is known ...
BACKGROUND: Chronic kidney disease (CKD) is associated with an increased mortality rate, risk of car...
Abstract Background Renal function decreases with age. Dosage adjustment according to renal function...
PURPOSE: The use of estimated glomerular filtration rate (eGFR) in daily clinical practice. METHODS:...
BACKGROUND: In older patients, the agreement is low between creatinine clearance estimated with the ...
BACKGROUND: Chronic kidney disease (CKD) is a growing problem among the elderly. Early detection is ...
Background: Chronic kidney disease (CKD) affects drug elimination and patients with CKD require appr...
Introduction: Reduced estimated creatinine clearance (eCrCl) is prevalent in older patients and impa...
Background: Drug-related problems are common in older people. Often they are related to low estimate...
BACKGROUND: The Modification of Diet in Renal Disease (MDRD) formula is widely used in clinical prac...
The Modification of Diet in Renal Disease (MDRD) formula is widely used in clinical practice to asse...
ObjectivesTo determine how many ambulatory older adults with chronic kidney disease receive medicati...
Aging with multimorbidity and polytherapy are the most significant factors that could led to inappro...
ABSTRACT: BACKGROUND: Renal function decreases with age. Dosage adjustment according to renal functi...
BACKGROUND: Kidney function reduces with age, increasing the risk of harm from increased blood level...
The aging process is characterized by relevant changes in pharmacokinetics. Renal function is known ...
BACKGROUND: Chronic kidney disease (CKD) is associated with an increased mortality rate, risk of car...
Abstract Background Renal function decreases with age. Dosage adjustment according to renal function...
PURPOSE: The use of estimated glomerular filtration rate (eGFR) in daily clinical practice. METHODS:...
BACKGROUND: In older patients, the agreement is low between creatinine clearance estimated with the ...
BACKGROUND: Chronic kidney disease (CKD) is a growing problem among the elderly. Early detection is ...
Background: Chronic kidney disease (CKD) affects drug elimination and patients with CKD require appr...
Introduction: Reduced estimated creatinine clearance (eCrCl) is prevalent in older patients and impa...
Background: Drug-related problems are common in older people. Often they are related to low estimate...
BACKGROUND: The Modification of Diet in Renal Disease (MDRD) formula is widely used in clinical prac...
The Modification of Diet in Renal Disease (MDRD) formula is widely used in clinical practice to asse...
ObjectivesTo determine how many ambulatory older adults with chronic kidney disease receive medicati...
Aging with multimorbidity and polytherapy are the most significant factors that could led to inappro...