Three new alkaloids, 15b-dehydro-5-N-acetylardeemin (3), 10-phenyl-[12]-cytochalasins Z16 (6) andZ17(7), were characterized from the liquid culture of the endophytic fungus Aspergillus terreus IFB-E030 along with six known derivatives, 5-N-acetylardeemin (1), 15b-beta-hydroxyl-5-N-acetylardeemin (2), cytochalasin E (4), rosellichalasin (5), cytochalasins Z11 (8), and Z13 (9). The structures of the new metabolites were established mainly by a combination of their 1D- and 2D-NMR spectra, single crystal X-ray diffraction, and the modified Mosher reaction. Biological assays indicated that cytochalasin Z17 (7) had moderate cytotoxicity against human nasopharyngeal epidermoid tumor KB cell line with an IC(50) value of 26.2 mu M
Ten new cytochalasan alkaloids, termed armochaetoglobins A–J (<b>1</b>–<b>10</b>), and four known ch...
Endophytes have been shown to be a source of novel drug prototypes. The Casearia genus is known for ...
A new cytochalasan named as phomocytochalasin (1), together with five previously identified compound...
Three new cytochalasans, named cytochalasins Z1, Z2 and Z3, were isolated from the wheat culture of ...
Eight new cytochalasins 1–8 and ten known analogs 9–18 were isolated from the endophytic fungus Phom...
Four new cytochalasans, phychaetoglobins A–D (1–4), together with twelve known cytochalasans (5–16),...
The cocultivation of <i>Aspergillus flavipes</i> and <i>Chaetomium globosum</i>, rich sources of cyt...
Aspergillus is one of the most diverse genera, and it is chemically profound and known to produce ma...
Chemical investigation of an acetonitrile fraction from the endophytic fungus Phomopsis sp. led to t...
Shu, Yan, Wang, Jia-Peng, Li, Bing-Xian, Gan, Jun-Li, Ding, Hao, Liu, Rui, Cai, Le, Ding, Zhong-Tao ...
Cytoglobosins H (1) and I (2), together with seven known cytochalasan alkaloids (3–9), were isolated...
<p>One new cytochalasin metabolite [11]-cytochalasa-5(6),13-diene-1,21-dione-7,18-dihydroxy-16,18-di...
A new cytochalasin, named cytochalasin P-1 (1), together with four known analogs (2-5) was isolated ...
A series of cytochalasins (1-6), including a new one (1), were isolated from the ethyl acetate extra...
A chemical study on the EtOAc extract produced by Xylaria sp., an endophytic fungus from Piper adunc...
Ten new cytochalasan alkaloids, termed armochaetoglobins A–J (<b>1</b>–<b>10</b>), and four known ch...
Endophytes have been shown to be a source of novel drug prototypes. The Casearia genus is known for ...
A new cytochalasan named as phomocytochalasin (1), together with five previously identified compound...
Three new cytochalasans, named cytochalasins Z1, Z2 and Z3, were isolated from the wheat culture of ...
Eight new cytochalasins 1–8 and ten known analogs 9–18 were isolated from the endophytic fungus Phom...
Four new cytochalasans, phychaetoglobins A–D (1–4), together with twelve known cytochalasans (5–16),...
The cocultivation of <i>Aspergillus flavipes</i> and <i>Chaetomium globosum</i>, rich sources of cyt...
Aspergillus is one of the most diverse genera, and it is chemically profound and known to produce ma...
Chemical investigation of an acetonitrile fraction from the endophytic fungus Phomopsis sp. led to t...
Shu, Yan, Wang, Jia-Peng, Li, Bing-Xian, Gan, Jun-Li, Ding, Hao, Liu, Rui, Cai, Le, Ding, Zhong-Tao ...
Cytoglobosins H (1) and I (2), together with seven known cytochalasan alkaloids (3–9), were isolated...
<p>One new cytochalasin metabolite [11]-cytochalasa-5(6),13-diene-1,21-dione-7,18-dihydroxy-16,18-di...
A new cytochalasin, named cytochalasin P-1 (1), together with four known analogs (2-5) was isolated ...
A series of cytochalasins (1-6), including a new one (1), were isolated from the ethyl acetate extra...
A chemical study on the EtOAc extract produced by Xylaria sp., an endophytic fungus from Piper adunc...
Ten new cytochalasan alkaloids, termed armochaetoglobins A–J (<b>1</b>–<b>10</b>), and four known ch...
Endophytes have been shown to be a source of novel drug prototypes. The Casearia genus is known for ...
A new cytochalasan named as phomocytochalasin (1), together with five previously identified compound...