Enantioselective synthesis of 16-membered trilactone macrolides, macrosphelide A and E from (S)-lactic acid is described. Key features of the synthesis include the utility of a hitherto unexplored beta-ketophosphonate derived from lactic acid and Yamaguchi lactonization leading to the title compounds. (C) 2011 Elsevier Ltd. All rights reserved
The thesis describes the synthesis and application of various alkynones derived from the bis-Weinreb...
Both epimers at C-21 in the proposed structure of (+)-callyspongiolide have been synthesized in a co...
A new strategy for enantioselective assembly of the trisubstituted tetrahydrofuran ring has been est...
Enantioselective synthesis of 16-membered trilactone macrolides, macrosphelide A and E from (S)-lact...
A formal total synthesis of the marine macrolide iriomoteolide3a is described. Salient features of t...
The enantiospecific total synthesis of 14-membered macrolactone Sch 725674 was accomplished from tar...
The enantiospecific total synthesis of 14-membered macrolactone Sch 725674 was accomplished from tar...
An enantioselective total synthesis of Sch-725674, a unique 14-membered macrolactone, has been accom...
A total, stereoselective synthesis of the cytotoxic macrolide aspergillide B has been performed. A c...
Total synthesis of macrosphelides is summarized. Synthetic approaches contain the preparation of key...
The enantiospecific total synthesis of 14-membered macrolactone Sch 725674 was accomplished from tar...
An enantioselective and convergent synthesis of the C7-C24 fragment of Macrolactin F was achieved fr...
An enantioselective synthesis of the macrolactone core of natural product Sch725674 was accomplished...
A concise total synthesis of the macrolactone natural product Sch 725674 is accomplished starting fr...
Stereoselective approach for the synthesis of both enantiomers of bio-active decanolactone microcarp...
The thesis describes the synthesis and application of various alkynones derived from the bis-Weinreb...
Both epimers at C-21 in the proposed structure of (+)-callyspongiolide have been synthesized in a co...
A new strategy for enantioselective assembly of the trisubstituted tetrahydrofuran ring has been est...
Enantioselective synthesis of 16-membered trilactone macrolides, macrosphelide A and E from (S)-lact...
A formal total synthesis of the marine macrolide iriomoteolide3a is described. Salient features of t...
The enantiospecific total synthesis of 14-membered macrolactone Sch 725674 was accomplished from tar...
The enantiospecific total synthesis of 14-membered macrolactone Sch 725674 was accomplished from tar...
An enantioselective total synthesis of Sch-725674, a unique 14-membered macrolactone, has been accom...
A total, stereoselective synthesis of the cytotoxic macrolide aspergillide B has been performed. A c...
Total synthesis of macrosphelides is summarized. Synthetic approaches contain the preparation of key...
The enantiospecific total synthesis of 14-membered macrolactone Sch 725674 was accomplished from tar...
An enantioselective and convergent synthesis of the C7-C24 fragment of Macrolactin F was achieved fr...
An enantioselective synthesis of the macrolactone core of natural product Sch725674 was accomplished...
A concise total synthesis of the macrolactone natural product Sch 725674 is accomplished starting fr...
Stereoselective approach for the synthesis of both enantiomers of bio-active decanolactone microcarp...
The thesis describes the synthesis and application of various alkynones derived from the bis-Weinreb...
Both epimers at C-21 in the proposed structure of (+)-callyspongiolide have been synthesized in a co...
A new strategy for enantioselective assembly of the trisubstituted tetrahydrofuran ring has been est...