The use of 7-deoxycholic acid as a chiral template in the asymmetric syntheses of 1,1'-binaphthyl-2,2'-diol derivatives is reported. Intramolecular coupling of compounds 7 and 11 have been carried out with Mn(acac)(3) in CH3CN to afford coupled binaphthol products 8 and 12 with 65% and >99% diastereoselectivity, respectively. In both cases the predominant formation of the (S) isomers were predicted by computer modeling studies. This was confirmed in the case of compound 12
A new concept of diastereomeric resolution has been developed where a boronic acid functionality was...
A novel synthetic strategy toward the asymmetric synthesis of vicinal diols bearing a tertiary cente...
The work to be presented herein illustrates several important facts. First, the synthesis of BIBOL ...
The use of 7-deoxycholic acid as a chiral template in the asymmetric syntheses of 1,1'-binaphthyl-2,...
The use of 7-deoxycholic acid as a chiral template in the asymmetric syntheses of 1,1'-binaphthyl-2,...
An oxidative binaphthol coupling with 65% yield and 65% selectivity has been accomplished using 7-de...
An oxidative binaphthol coupling with 65% yield and 65% selectivity has been accomplished using 7-de...
An invention of new catalytic strategies for stereoselective synthesis is of current interest to ma...
1,1’-Binaphthyl and its derivatives represent a particular class of chemical molecules which chirali...
Synthesis of enantiomerically pure compounds by the use of “man made” chiral inducers has the greate...
The V(II) promoted pinacol cross coupling of a chiral aromatic aldehyde with chiral aliphatic aldehy...
8 1 INTRODUCTION Over the last two decades, high-performance liquid chromatography (HPLC) has become...
A series of new 1,1'-bi-2-naphthol (BINOL) derived ligands, 3-[6-(hydroxymethyl)pyridin-2-yl]-BINOLs...
The use of chiral counterions to facilitate enantioselective mono-C-alkylation of enolates has been...
Bile acids are natural products that are located within a variety of organisms through metabolism of...
A new concept of diastereomeric resolution has been developed where a boronic acid functionality was...
A novel synthetic strategy toward the asymmetric synthesis of vicinal diols bearing a tertiary cente...
The work to be presented herein illustrates several important facts. First, the synthesis of BIBOL ...
The use of 7-deoxycholic acid as a chiral template in the asymmetric syntheses of 1,1'-binaphthyl-2,...
The use of 7-deoxycholic acid as a chiral template in the asymmetric syntheses of 1,1'-binaphthyl-2,...
An oxidative binaphthol coupling with 65% yield and 65% selectivity has been accomplished using 7-de...
An oxidative binaphthol coupling with 65% yield and 65% selectivity has been accomplished using 7-de...
An invention of new catalytic strategies for stereoselective synthesis is of current interest to ma...
1,1’-Binaphthyl and its derivatives represent a particular class of chemical molecules which chirali...
Synthesis of enantiomerically pure compounds by the use of “man made” chiral inducers has the greate...
The V(II) promoted pinacol cross coupling of a chiral aromatic aldehyde with chiral aliphatic aldehy...
8 1 INTRODUCTION Over the last two decades, high-performance liquid chromatography (HPLC) has become...
A series of new 1,1'-bi-2-naphthol (BINOL) derived ligands, 3-[6-(hydroxymethyl)pyridin-2-yl]-BINOLs...
The use of chiral counterions to facilitate enantioselective mono-C-alkylation of enolates has been...
Bile acids are natural products that are located within a variety of organisms through metabolism of...
A new concept of diastereomeric resolution has been developed where a boronic acid functionality was...
A novel synthetic strategy toward the asymmetric synthesis of vicinal diols bearing a tertiary cente...
The work to be presented herein illustrates several important facts. First, the synthesis of BIBOL ...