One-pot synthesis of 2-chloronicotinonitriles and fused 2-chloro-3-cyanopyridines

Sreenivasulu, M
Rao, Krishna GS

Publication date

January 1989

Publisher

National Institute of Science Communication and Information Resources

Abstract

Vilsmeier reaction (POCl3, Me2NHCHO) of alkylidenemalononitriles gives the title compds. by in situ generation of an aldehyde equiv. followed by cyclization. E.g., PrCH:C(CN)2 gives 19% chloroethylnicotinonitrile I

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One-pot synthesis of 2-chloronicotinonitriles and fused 2-chloro-3-cyanopyridines

Abstract

Extracted data

One-pot synthesis of 2-chloronicotinonitriles and fused 2-chloro-3-cyanopyridines

Abstract

Extracted data

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