The development of two-dimensional proton-proton nuclear Overhauser effect spectroscopy was a seminal development in the algorithm of protein structure determination by liquid-state NMR. This article provides a historical and personal view of the various facilities, challenges and solutions in the successful development of this experiment for biomolecules in Professor Wuthrich's laboratory during the academic year 1979-80
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...
The development of two-dimensional proton-proton nuclear Overhauser effect spectroscopy was a semina...
It is demonstrated, by means of experiments with the basic pancreatic trypsin inhibitor, that the bu...
It is demonstrated, by means of experiments with the basic pancreatic trypsin inhibitor, that the bu...
During the last 5 years, since its first application to biomolecules, twodimensional nuclear Overhau...
During the last 5 years, since its first application to biomolecules, twodimensional nuclear Overhau...
During the last 5 years, since its first application to biomolecules, twodimensional nuclear Overhau...
The principles, theory, and applications of the transferred proton-proton nuclear Overhauser effect ...
This paper describes a new nuclear magnetic resonance approach for the determination of secondary st...
AbstractA systematic procedure is outlined to reveal assignments in the 1H NMR spectrum of a protein...
The measurement of nuclear Overhauser effects (1) for determination of the three-dimensional structu...
This paper demonstrates that two-dimensional (2D) NMR experiments are particularly suitable for stud...
Highly selective and efficient water signal suppression is indispensable in biomolecular 2D nuclear ...
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...
The development of two-dimensional proton-proton nuclear Overhauser effect spectroscopy was a semina...
It is demonstrated, by means of experiments with the basic pancreatic trypsin inhibitor, that the bu...
It is demonstrated, by means of experiments with the basic pancreatic trypsin inhibitor, that the bu...
During the last 5 years, since its first application to biomolecules, twodimensional nuclear Overhau...
During the last 5 years, since its first application to biomolecules, twodimensional nuclear Overhau...
During the last 5 years, since its first application to biomolecules, twodimensional nuclear Overhau...
The principles, theory, and applications of the transferred proton-proton nuclear Overhauser effect ...
This paper describes a new nuclear magnetic resonance approach for the determination of secondary st...
AbstractA systematic procedure is outlined to reveal assignments in the 1H NMR spectrum of a protein...
The measurement of nuclear Overhauser effects (1) for determination of the three-dimensional structu...
This paper demonstrates that two-dimensional (2D) NMR experiments are particularly suitable for stud...
Highly selective and efficient water signal suppression is indispensable in biomolecular 2D nuclear ...
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...
[Introduction in lieu of Abstract] The development of magnetic multiple resonance during the past ye...