Add to ORKGThe structure networks of DNA-binding proteins have been constructed and analyzed. The detailed analysis of the networks indicates a strong relation between the positions of the residues interacting with DNA and those that form extensive interactions within the protein structure (called hubs). This study shows that the functional residues in these proteins are held in place by efficient scaffolding of the structure using sidechain interactions, thus highlighting the role of these side-chain hubs with respect to the functional residues in the protein structure
Charles University in Prague Faculty of Science Department of Physical and Macromolecular Chemistry ...
The three-dimensional structure of a protein is formed and maintained by the noncovalent interaction...
This study views each protein structure as a network of noncovalent connections between amino acid s...
The structure networks of DNA-binding proteins have been constructed and analyzed. The detailed anal...
Protein–DNA interactions facilitate the fundamental functions of living cells and are universal in a...
Protein–DNA interactions facilitate the fundamental functions of living cells and are universal in a...
Protein-DNA interactions facilitate the fundamental functions of living cells and are universal in a...
Protein–DNA interactions facilitate the fundamental functions of living cells and are universal in a...
Protein-DNA interactions are crucial for many cellular processes. Now with the increased availabilit...
Proteins that bind DNA are fundamental to all areas of genetic activity within the cell. To understa...
Understanding the role proteins play in regulating DNA replication is essential to forming a complet...
Amino acid residues, which play important roles in protein function, are often conserved. Here, we a...
Network analysis is a computational approach used to describe the structure and dynamics of complex ...
Using a new representation for interactions in protein sequences based on correlations between pairs...
Network analysis is a computational approach used to describe the structure and dynamics of complex ...
Charles University in Prague Faculty of Science Department of Physical and Macromolecular Chemistry ...
The three-dimensional structure of a protein is formed and maintained by the noncovalent interaction...
This study views each protein structure as a network of noncovalent connections between amino acid s...
The structure networks of DNA-binding proteins have been constructed and analyzed. The detailed anal...
Protein–DNA interactions facilitate the fundamental functions of living cells and are universal in a...
Protein–DNA interactions facilitate the fundamental functions of living cells and are universal in a...
Protein-DNA interactions facilitate the fundamental functions of living cells and are universal in a...
Protein–DNA interactions facilitate the fundamental functions of living cells and are universal in a...
Protein-DNA interactions are crucial for many cellular processes. Now with the increased availabilit...
Proteins that bind DNA are fundamental to all areas of genetic activity within the cell. To understa...
Understanding the role proteins play in regulating DNA replication is essential to forming a complet...
Amino acid residues, which play important roles in protein function, are often conserved. Here, we a...
Network analysis is a computational approach used to describe the structure and dynamics of complex ...
Using a new representation for interactions in protein sequences based on correlations between pairs...
Network analysis is a computational approach used to describe the structure and dynamics of complex ...
Charles University in Prague Faculty of Science Department of Physical and Macromolecular Chemistry ...
The three-dimensional structure of a protein is formed and maintained by the noncovalent interaction...
This study views each protein structure as a network of noncovalent connections between amino acid s...