Background: There is clinical and experimental evidence for altered adenosine signalling in the fetoplacental circulation in pregnancies complicated by diabetes, leading to adenosine accumulation in the placenta. However, the consequence for fetoplacental vasocontractility is unclear. This study examined contractility to adenosine of chorionic vessels from type 1 diabetes mellitus, gestational diabetes mellitus and normal pregnancies.Methods: Chorionic arteries and veins were isolated from human placenta from normal, gestational diabetes mellitus and type 1 diabetes mellitus pregnancies. Isometric tension recording measured responses to adenosine and the thromboxane A2 analogue U46619 (thromboxane A2 mediates adenosine fetoplacental vasocon...
Pregnancy complicated by diabetes is a relatively frequent event and may result in fetal embriopathy...
Gestational diabetes mellitus (GDM) courses with increased fetal plasma adenosine concentration and ...
Pregnancy involves a physiological series of actions which necessitate a coordinated transformation ...
Background: There is clinical and experimental evidence for altered adenosine signalling in the feto...
Gestational diabetes mellitus (GDM) is a pregnancy disease characterized by maternal high blood gluc...
Gestational diabetes mellitus (GDM) is a detrimental condition for human pregnancy associated with e...
Gestational diabetes mellitus (GDM) is a pregnancy disease characterized by maternal high blood gluc...
Gestational diabetes mellitus (GDM) is a disease of pregnancy associated with maternal and foetal hy...
Introduction Preeclampsia is associated with impaired placental vasodilation and reduced endothelial...
Regulation of blood flow depends on the systemic and local release of vasoactive molecules including...
Supplemental material, dvdres-feb-2018-00026-File011 for Impaired vasocontractile responses to adeno...
Supplemental material, dvdres-feb-2018-00026-File012 for Impaired vasocontractile responses to adeno...
Gestational diabetes mellitus (GDM) is a syndrome compromising the health of the mother and the fetu...
Supplemental material, dvdres-feb-2018-00026-File010 for Impaired vasocontractile responses to adeno...
Gestational diabetes mellitus (GDM) courses with increased fetal plasma adenosine concentration and ...
Pregnancy complicated by diabetes is a relatively frequent event and may result in fetal embriopathy...
Gestational diabetes mellitus (GDM) courses with increased fetal plasma adenosine concentration and ...
Pregnancy involves a physiological series of actions which necessitate a coordinated transformation ...
Background: There is clinical and experimental evidence for altered adenosine signalling in the feto...
Gestational diabetes mellitus (GDM) is a pregnancy disease characterized by maternal high blood gluc...
Gestational diabetes mellitus (GDM) is a detrimental condition for human pregnancy associated with e...
Gestational diabetes mellitus (GDM) is a pregnancy disease characterized by maternal high blood gluc...
Gestational diabetes mellitus (GDM) is a disease of pregnancy associated with maternal and foetal hy...
Introduction Preeclampsia is associated with impaired placental vasodilation and reduced endothelial...
Regulation of blood flow depends on the systemic and local release of vasoactive molecules including...
Supplemental material, dvdres-feb-2018-00026-File011 for Impaired vasocontractile responses to adeno...
Supplemental material, dvdres-feb-2018-00026-File012 for Impaired vasocontractile responses to adeno...
Gestational diabetes mellitus (GDM) is a syndrome compromising the health of the mother and the fetu...
Supplemental material, dvdres-feb-2018-00026-File010 for Impaired vasocontractile responses to adeno...
Gestational diabetes mellitus (GDM) courses with increased fetal plasma adenosine concentration and ...
Pregnancy complicated by diabetes is a relatively frequent event and may result in fetal embriopathy...
Gestational diabetes mellitus (GDM) courses with increased fetal plasma adenosine concentration and ...
Pregnancy involves a physiological series of actions which necessitate a coordinated transformation ...