Interventions to improve retention in a surgical, clinical trial: a pragmatic, stakeholder driven approach

ObjectiveTo explore stakeholder perspectives upon participant retention in clinical trials, and to generate strategies to support retention in a surgical, clinical trial.Study Design & SettingThe SWIFFT trial is a multi-centre study comparing treatments for the fracture of the waist of the scaphoid bone in adults. Here we report upon a multi-stage, iterative consultative process with SWIFFT stakeholders, these include workshops with members of the public, with nurses involved in data collection, and with consultant clinicians. Structured discussions were digitally recorded and transcribed, data were handled and analysed following a framework approach to qualitative data analysis.ResultsRemoving practical barriers were identified as important factors in supporting retention. Stakeholders also identified that i) how well a study is understood and ii) how much it is valued are important factors in an individual’s willingness to maintain their involvement. A number of strategies resulted from this consultation, these include: in-clinic data collection, co-ordinated clinical and research appointments, a SWIFFT website and newsletter. ConclusionA participatory approach to trial retention might engage all relevant stakeholders in the delivery of a clinical trial, it might also support the generation of specific and contextually relevant solutions to the challenge of participant retention