The cyclopropane ring is ubiquitous in natural and biologically active compounds. [3,3]-Sigmatropic rearrangements of cyclopropenylcarbinol derivatives have been developed to access functionalized alkylidenecyclopropanes, which are useful precursors of diversely substituted cyclopropanes. We have shown that the rearrangement of cyclopropenylcarbinyl cyanates could be accomplished under mild conditions to obtain N-acyl alkylidene(aminocyclopropanes). The Ireland–Claisen rearrangement of glycolates or glycinates derived from secondary cyclopropenylcarbinols has been developed as an efficient and stereoselective method for the synthesis of alkylidenecyclopropanes possessing an α-hydroxy or α-amino acid moiety. The scope of this transformation ...
This Thesis is focused on the preparation of organic molecules that contain a three-membered ring sy...
In this account, we elaborate our group's contribution towards understanding the chemistry of carboh...
A route to 1,2,3-trisubstituted cyclopropanes has been developed. The relative stereochemistry at th...
Les cyclopropanes sont rencontrés dans de nombreux produits naturels ou synthétiques bioactifs. Les ...
Cyclopropenes constitute useful precursors of other classes of compounds incorporating a three-membe...
A one-pot difluorocyclopropenation/Ireland–Claisen rearrangement sequence applied to readily availab...
This thesis describes the generation and reactivity of functionalised organozinc carbenoids for cycl...
A stereoselective route to cis-2-(2′-carboxycyclopropyl)glycine has been developed. exo-Nucleophilic...
Graduation date: 2005The rearrangement of a homoallyl cation to a cyclopropylcarbinyl cation is\ud t...
Cyclopropanes are encountered in several natural and synthetic products displaying a wide range of b...
The combination of cyclopropanes and carbohydrates functionality within a single molecule gives the ...
Les cyclopropanes sont des motifs d’une grande importance puisqu’ils sont présents dans plusieurs mo...
The cyclopropane moiety is found in a wide variety of the natural products, from small amino acid mo...
The cyclopropane moiety is found in a wide variety of the natural products, from small amino acid mo...
Activated cyclopropanes have been extensively used in synthetic chemistry as precursors for cycloadd...
This Thesis is focused on the preparation of organic molecules that contain a three-membered ring sy...
In this account, we elaborate our group's contribution towards understanding the chemistry of carboh...
A route to 1,2,3-trisubstituted cyclopropanes has been developed. The relative stereochemistry at th...
Les cyclopropanes sont rencontrés dans de nombreux produits naturels ou synthétiques bioactifs. Les ...
Cyclopropenes constitute useful precursors of other classes of compounds incorporating a three-membe...
A one-pot difluorocyclopropenation/Ireland–Claisen rearrangement sequence applied to readily availab...
This thesis describes the generation and reactivity of functionalised organozinc carbenoids for cycl...
A stereoselective route to cis-2-(2′-carboxycyclopropyl)glycine has been developed. exo-Nucleophilic...
Graduation date: 2005The rearrangement of a homoallyl cation to a cyclopropylcarbinyl cation is\ud t...
Cyclopropanes are encountered in several natural and synthetic products displaying a wide range of b...
The combination of cyclopropanes and carbohydrates functionality within a single molecule gives the ...
Les cyclopropanes sont des motifs d’une grande importance puisqu’ils sont présents dans plusieurs mo...
The cyclopropane moiety is found in a wide variety of the natural products, from small amino acid mo...
The cyclopropane moiety is found in a wide variety of the natural products, from small amino acid mo...
Activated cyclopropanes have been extensively used in synthetic chemistry as precursors for cycloadd...
This Thesis is focused on the preparation of organic molecules that contain a three-membered ring sy...
In this account, we elaborate our group's contribution towards understanding the chemistry of carboh...
A route to 1,2,3-trisubstituted cyclopropanes has been developed. The relative stereochemistry at th...