Variability induced by the MR imager in dynamic contrast-enhanced imaging of the prostate
- Brunelle, S.
- Zemmour, C.
- Bratan, F.
- Mège-Lechevallier, F.
- Ruffion, A.
- Colombel, M.
- Crouzet, S.
- Sarran, A.
- Rouvière, O.
DOIAbstract
International audiencePURPOSE:To evaluate the variability induced by the imager in discriminating high-grade (Gleason≥7) prostate cancers (HGC) using dynamic contrast-enhanced MRI.MATERIAL AND METHODS:We retrospectively selected 3T MRIs with temporal resolution<10 seconds and comprising T1 mapping from a prospective radiologic-pathologic database of patients treated by prostatectomy. Ktrans, Kep, Ve and Vp were calculated for each lesion seen on MRI using the Weinmann arterial input function (AIF) and three patient-specific AIFs measured in the right and left iliac arteries in pixels in the center of the lumen (psAIF-ST) or manually selected by two independent readers (psAIF-R1 and psAIF-R2).RESULTS:A total of 43 patients (mean age, 63.6±4....
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