We conducted a systematic review and meta-analysis of studies reporting circulating IL-6 in AAA, and new investigations of the association between a common non-synonymous functional variant (Asp358Ala) in the IL-6R gene (IL6R) and AAA, followed the analysis of the variant both in vitro and in vivo. Inflammation may play a role in the development of abdominal aortic aneurysms (AAA). Interleukin-6 (IL-6) signalling through its receptor (IL-6R) is one pathway that could be exploited pharmacologically. We investigated this using a Mendelian randomization approach
Although the pathogenesis of abdominal aortic aneurysm (AAA) remains unclear, evidence is accumulati...
ObjectiveCirculating plasma interleukin-6 (IL-6) concentrations are elevated in patients with abdomi...
BACKGROUND: The formation of abdominal aortic aneurysms (AAA) is characterized by a dominance of ...
MethodsWe conducted a systematic review and meta-analysis of studies reporting circulating IL-6 in A...
Methods We conducted a systematic review and meta-analysis of studies reporting circulating IL-6 in ...
METHODS: We conducted a systematic review and meta-analysis of studies reporting circulating IL-6 in...
textabstractMethodsWe conducted a systematic review and meta-analysis of studies reporting circulati...
BACKGROUND: The Asp358Ala variant (rs2228145; A>C) in the IL (interleukin)-6 receptor ( IL6R) gene h...
Background: The Asp358Ala variant (rs2228145; A>C) in the IL (interleukin)-6 receptor (IL6R) gene ha...
Background: The Asp358Ala variant (rs2228145; A>C) in the interleukin-6 receptor (IL6R) gene has bee...
BackgroundElevated levels of circulating interleukin-6 (IL-6) have been reported in patients with ab...
AbstractBackground and aimsAn abdominal aortic aneurysm (AAA) is part of the atherosclerotic spectru...
AbstractBackground and aimsAn abdominal aortic aneurysm (AAA) is part of the atherosclerotic spectru...
BackgroundElevated levels of circulating interleukin-6 (IL-6) have been reported in patients with ab...
Background: Elevated levels of circulating interleukin-6 (IL-6) have been reported in patients with ...
Although the pathogenesis of abdominal aortic aneurysm (AAA) remains unclear, evidence is accumulati...
ObjectiveCirculating plasma interleukin-6 (IL-6) concentrations are elevated in patients with abdomi...
BACKGROUND: The formation of abdominal aortic aneurysms (AAA) is characterized by a dominance of ...
MethodsWe conducted a systematic review and meta-analysis of studies reporting circulating IL-6 in A...
Methods We conducted a systematic review and meta-analysis of studies reporting circulating IL-6 in ...
METHODS: We conducted a systematic review and meta-analysis of studies reporting circulating IL-6 in...
textabstractMethodsWe conducted a systematic review and meta-analysis of studies reporting circulati...
BACKGROUND: The Asp358Ala variant (rs2228145; A>C) in the IL (interleukin)-6 receptor ( IL6R) gene h...
Background: The Asp358Ala variant (rs2228145; A>C) in the IL (interleukin)-6 receptor (IL6R) gene ha...
Background: The Asp358Ala variant (rs2228145; A>C) in the interleukin-6 receptor (IL6R) gene has bee...
BackgroundElevated levels of circulating interleukin-6 (IL-6) have been reported in patients with ab...
AbstractBackground and aimsAn abdominal aortic aneurysm (AAA) is part of the atherosclerotic spectru...
AbstractBackground and aimsAn abdominal aortic aneurysm (AAA) is part of the atherosclerotic spectru...
BackgroundElevated levels of circulating interleukin-6 (IL-6) have been reported in patients with ab...
Background: Elevated levels of circulating interleukin-6 (IL-6) have been reported in patients with ...
Although the pathogenesis of abdominal aortic aneurysm (AAA) remains unclear, evidence is accumulati...
ObjectiveCirculating plasma interleukin-6 (IL-6) concentrations are elevated in patients with abdomi...
BACKGROUND: The formation of abdominal aortic aneurysms (AAA) is characterized by a dominance of ...