Axial structures (neural tube/notochord) and surface ectoderm activate myogenesis in the mouse embryo; their action can be reproduced, at least in part, by several molecules such as Sonic hedgehog and Wnts, Recently, soluble Wnt antagonists have been identified, Among those examined only Frzb1 was found to be expressed in the presomitic mesoderm and newly formed somites and thus its possible role in regulating myogenesis was investigated in detail, When presomitic mesoderm or newly formed somites were cultured with axial structures and surface ectoderm on a feeder layer of C3H10T1/2 cells expressing Frzb1, myogenesis was abolished or severely reduced in presomitic mesoderm and the three most recently formed somites, In contrast, no effect w...
Differential gene regulation integrated in time and space drives developmental programs during embry...
Signaling molecules play essential roles in communication between cells. Wnt signaling molecules ar...
AbstractWnt-3amutant embryos show defects caudal to the forelimb level; somites are absent, the noto...
Axial structures (neural tube/notochord) and surface ectoderm activate myogenesis in the mouse embry...
In the amniote embryos, specification of skeletal myoblasts occurs in the paraxial mesoderm in respo...
In the amniote embryos, specification of skeletal myo-blasts occurs in the paraxial mesoderm in resp...
The Wnt family of secreted signaling molecules is conserved throughout the animal kingdom. Wnt signa...
The Wnt genes are known to play fundamental roles during patterning and development of a number of e...
AbstractMuscles of the body and bones of the axial skeleton derive from specialized regions of somit...
Frzb-1 is a secreted protein containing a domain similar to the putative Wnt-binding region of the f...
Activation of myogenesis in newly formed somites is dependent upon signals derived from neighboring ...
AbstractFrzb-1 is a secreted protein containing a domain similar to the putative Wnt-binding region ...
The expression of eight murine Frizzled (1,3-9) genes was studied during mouse somitogenesis, in ord...
AbstractThe Wnt genes are known to play fundamental roles during patterning and development of a num...
Wnts are highly conserved developmental regulators that mediate inductive signaling between neighbor...
Differential gene regulation integrated in time and space drives developmental programs during embry...
Signaling molecules play essential roles in communication between cells. Wnt signaling molecules ar...
AbstractWnt-3amutant embryos show defects caudal to the forelimb level; somites are absent, the noto...
Axial structures (neural tube/notochord) and surface ectoderm activate myogenesis in the mouse embry...
In the amniote embryos, specification of skeletal myoblasts occurs in the paraxial mesoderm in respo...
In the amniote embryos, specification of skeletal myo-blasts occurs in the paraxial mesoderm in resp...
The Wnt family of secreted signaling molecules is conserved throughout the animal kingdom. Wnt signa...
The Wnt genes are known to play fundamental roles during patterning and development of a number of e...
AbstractMuscles of the body and bones of the axial skeleton derive from specialized regions of somit...
Frzb-1 is a secreted protein containing a domain similar to the putative Wnt-binding region of the f...
Activation of myogenesis in newly formed somites is dependent upon signals derived from neighboring ...
AbstractFrzb-1 is a secreted protein containing a domain similar to the putative Wnt-binding region ...
The expression of eight murine Frizzled (1,3-9) genes was studied during mouse somitogenesis, in ord...
AbstractThe Wnt genes are known to play fundamental roles during patterning and development of a num...
Wnts are highly conserved developmental regulators that mediate inductive signaling between neighbor...
Differential gene regulation integrated in time and space drives developmental programs during embry...
Signaling molecules play essential roles in communication between cells. Wnt signaling molecules ar...
AbstractWnt-3amutant embryos show defects caudal to the forelimb level; somites are absent, the noto...