The deployment of special instrumentation for the Hydrological Cycle in the Mediterranean Experiment (HyMeX) provides a valuable opportunity to investigate the spatio-temporal variability of atmospheric water vapour across scales in relationship with the occurrence of Heavy Precipitation Systems (HPSs) in the north Western Mediterranean (WMed) during the Intensive Observation Period (IOP12), which is the focus of this investigation. High-resolution convection-permitting COSMO simulations complement the observational network and allow the calculation of on-line trajectories. In addition to the presence of a favourable large-scale situation and low-level convergence, atmospheric moisture changes resulting in conditionally unstable air are ide...