The interaction between the cytokine LIF and the neurotrophins on spiral ganglion cells [Abstract]

The survival of auditory neurones depends on the continuous supply of trophic factors. Hair cells within the cochlea are known to produce supply growth factors responsible for the survival and growth of The survival of auditory neurones depends on the continuous supply of trophic factors. Hair cells within the cochlea are known to produce supply growth factors responsible for the survival and growth of [ ] neurones. As a result of trauma, disease or ageing cochlear hair cells are lost, and consequently, the supply of growth factors is reduced, leading to secondary wave of auditory nerve degeneration.2-7 Marc