We thank the Development Trust, University of Aberdeen, for funding a fellowship to M.P. and a studentship to A.A. Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1590898.Peer reviewedPostprin
AbstractTwo new Drug Delivery Systems (DDS) cyclo[DKP‐isoDGR]‐PEG‐4‐Val‐Ala‐PTX (2) and cyclo[DKP‐is...
Herein we report the synthesis of three multimeric RGD peptidomimetic-paclitaxel conjugates featurin...
Tumor-targeting drug delivery systems are being the ideal carrier for systemic administration of ant...
A 1,2,3-triazole-based RGD peptidomimetic having nanomolar affinity for α v β 3 integrin was conjuga...
Integrins are a large family of heterodimeric transmembrane glycoprotein receptors, composed by two ...
The efficacy of taxane-based antitumor therapy is limited by several drawbacks which result in a poo...
Being overexpressed on blood vessels in human tumors, but not on vessels in normal human tissues, th...
The efficacy of taxane-based antitumor therapy is limited by several drawbacks which result in a poo...
The efficacy of taxane-based antitumor therapy is limited by several drawbacks which result in a poo...
Two cyclo[DKP-RGD]-PTX (PTX = paclitaxel) and two cyclo[RGDfK]-PTX conjugates containing the lysoso...
Abstract Nowadays, systemic administration of cytotoxic agents is one of the main keystones of moder...
Two small-molecule\u2013drug conjugates (SMDCs, 6 and 7) featuring lysosomally cleavable linkers (na...
A small library of integrin ligand - Paclitaxel conjugates 10-13 was synthesized with the aim of usi...
Conjugation of cytotoxic agents to targeting carriers (e.g. antibodies or small molecules) capable o...
Herein we report the first example of an isoDGR\u2013drug conjugate (2), designed to release paclita...
AbstractTwo new Drug Delivery Systems (DDS) cyclo[DKP‐isoDGR]‐PEG‐4‐Val‐Ala‐PTX (2) and cyclo[DKP‐is...
Herein we report the synthesis of three multimeric RGD peptidomimetic-paclitaxel conjugates featurin...
Tumor-targeting drug delivery systems are being the ideal carrier for systemic administration of ant...
A 1,2,3-triazole-based RGD peptidomimetic having nanomolar affinity for α v β 3 integrin was conjuga...
Integrins are a large family of heterodimeric transmembrane glycoprotein receptors, composed by two ...
The efficacy of taxane-based antitumor therapy is limited by several drawbacks which result in a poo...
Being overexpressed on blood vessels in human tumors, but not on vessels in normal human tissues, th...
The efficacy of taxane-based antitumor therapy is limited by several drawbacks which result in a poo...
The efficacy of taxane-based antitumor therapy is limited by several drawbacks which result in a poo...
Two cyclo[DKP-RGD]-PTX (PTX = paclitaxel) and two cyclo[RGDfK]-PTX conjugates containing the lysoso...
Abstract Nowadays, systemic administration of cytotoxic agents is one of the main keystones of moder...
Two small-molecule\u2013drug conjugates (SMDCs, 6 and 7) featuring lysosomally cleavable linkers (na...
A small library of integrin ligand - Paclitaxel conjugates 10-13 was synthesized with the aim of usi...
Conjugation of cytotoxic agents to targeting carriers (e.g. antibodies or small molecules) capable o...
Herein we report the first example of an isoDGR\u2013drug conjugate (2), designed to release paclita...
AbstractTwo new Drug Delivery Systems (DDS) cyclo[DKP‐isoDGR]‐PEG‐4‐Val‐Ala‐PTX (2) and cyclo[DKP‐is...
Herein we report the synthesis of three multimeric RGD peptidomimetic-paclitaxel conjugates featurin...
Tumor-targeting drug delivery systems are being the ideal carrier for systemic administration of ant...