Coxsackievirus and Type 1 Diabetes Mellitus: The Wolf's Footprints

Eizirik, Decio L.
Op De Beeck, Anne

Open link

Publication date

March 2018

DOI

10.1016/j.tem.2017.12.002

Publisher

Elsevier BV

Abstract

Enteroviruses are important environmental contributors to islet inflammation (insulitis) in type 1 diabetes mellitus (T1DM). A recent study characterized the proteomic alterations induced by Coxsackievirus type B (CVB) infection of human islets. This provides relevant information to decipher the words of the virus-induced ‘dialog’ between β cells and the immune system that leads to autoimmunity.SCOPUS: sh.jinfo:eu-repo/semantics/publishe