Discovery of a new azole resistance mechanism in Aspergillus fumigatus through whole genome sequencing and sexual crossing.

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
van Dijk, Karin
Hagen, Ferry
van der Beek, Martha T.
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J. G.
Verweij, Paul E.
Debets, Alfons J. M.

January 2017

This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two comp...

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

Zhang, J.
Snelders, E.
Zwaan, B.J.
Schoustra, S.E.
Meis, J.F.G.M.
Dijk, K van
Hagen, F.
Beek, M.T. van der
Kampinga, G.A.
Zoll, J.
Melchers, W.J.G.
Verweij, P.E.
Debets, A.J.

January 2017

This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two comp...

A novel environmental azole resistance mutation in Aspergillus fumigatus and a possible role of sexual reproduction in its emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
Van Dijk, Karin
Hagen, Ferry
Van Der Beek, Martha T.
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J.G.
Verweij, Paul E.
Debets, Alfons J.M.

May 2017

This study investigated the dynamics of Aspergillus fumigatus azoleresistant phenotypes in two compo...

Discovery of a hapE Mutation That Causes Azole Resistance in Aspergillus fumigatus through Whole Genome Sequencing and Sexual Crossing

Camps, S.M.T.
Dutilh, B.E.
Arendrup, M.C.
Rijs, A.J.M.M.
Snelders, E.
Huynen, M.A.
Verweij, P.E.
Melchers, W.J.G.

January 2012

Contains fulltext : 110931.pdf (publisher's version ) (Open Access)Azole compounds...

Molecular mechanisms of azole resistance in Aspergillus fumigatus

Camps, S.M.T.

January 2013

Contains fulltext : 112900.pdf (publisher's version ) (Open Access)Radboud Univers...

Discovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing.

Simone M T Camps
Bas E Dutilh
Maiken C Arendrup
Antonius J M M Rijs
Eveline Snelders
Martijn A Huynen
Paul E Verweij
Willem J G Melchers

Azole compounds are the primary therapy for patients with diseases caused by Aspergillus fumigatus. ...

Discovery of a hapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing. PLoS One 2012

Simone M. T. Camps
Bas E. Dutilh
Maiken C. Arendrup
Antonius J. M. M. Rijs
Eveline Snelders
Martijn A. Huynen
Paul E. Verweij
Willem J. G. Melchers

August 2016

Azole compounds are the primary therapy for patients with diseases caused by Aspergillus fumigatus. ...

Discovery of a hapE Mutation That Causes Azole Resistance in Aspergillus fumigatus through Whole Genome Sequencing and Sexual Crossing

Camps, Simone M.T.
Dutilh, Bas E.
Arendrup, Maiken C.
Rijs, Antonius J.M.M.
Snelders, Eveline
Huynen, Martijn A.
Verweij, Paul E.
Melchers, Willem J.G.

January 2012

Azole compounds are the primary therapy for patients with diseases caused by Aspergillus fumigatus. ...

Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing

Abdolrasouli, A.
Rhodes, J.
Beale, M.A.
Hagen, F.
Rogers, T.R.
Chowdhary, A.
Meis, J.F.G.M.
Armstrong-James, D.
Fisher, M.C.

January 2015

Contains fulltext : 155363.pdf (publisher's version ) (Open Access)A rapid and glo...

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

Zhang, J.
Snelders, E.
Zwaan, B.J.
Schoustra, S.E.
Meis, J.F.G.M.
Dijk, K van
Hagen, F.
Beek, M.T. van der
Kampinga, G.A.
Zoll, J.
Melchers, W.J.G.
Verweij, P.E.
Debets, A.J.

January 2017

Contains fulltext : 177560.pdf (publisher's version ) (Open Access)This study inve...

Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis.

Linden, J.W. van der
Arendrup, M.C.
Melchers, W.J.
Verweij, P.E.

January 2016

Contains fulltext : 171999.pdf (publisher's version ) (Open Access

Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing

Abdolrasouli, A.
Rhodes, J.
Beale, M.A.
Hagen, F.
Rogers, T.R.
Chowdhary, A.
Meis, J.F.G.M.
Armstrong-James, D.
Fisher, M.C.

January 2015

A rapid and global emergence of azole resistance has been observed in the pathogenic fungus Aspergil...

A novel environmental azole resistance mutation in Aspergillus fumigatus and a possible role of sexual reproduction in its emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
Dijk, Karin, van
Hagen, Ferry
Beek, Martha T., van der
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J.G.
Verweij, Paul E.
Debets, Fons

January 2017

This study investigated the dynamics of Aspergillus fumigatus azoleresistant phenotypes in two compo...

A novel environmental azole resistance mutation in Aspergillus fumigatus and a possible role of sexual reproduction in its emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
Dijk, van, Karin
Hagen, Ferry
Beek, van der, Martha T.
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J.G.
Verweij, Paul E.
Debets, Fons

January 2017

This study investigated the dynamics of Aspergillus fumigatus azoleresistant phenotypes in two compo...

Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling.

Snelders, E.
Karawajczyk, A.
Schaftenaar, G.
Verweij, P.E.
Melchers, W.J.G.

January 2010

Contains fulltext : 88470.pdf (publisher's version ) (Open Access)Molecular studie...

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
van Dijk, Karin
Hagen, Ferry
van der Beek, Martha T.
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J. G.
Verweij, Paul E.
Debets, Alfons J. M.

January 2017

This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two comp...

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

Zhang, J.
Snelders, E.
Zwaan, B.J.
Schoustra, S.E.
Meis, J.F.G.M.
Dijk, K van
Hagen, F.
Beek, M.T. van der
Kampinga, G.A.
Zoll, J.
Melchers, W.J.G.
Verweij, P.E.
Debets, A.J.

January 2017

This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two comp...

A novel environmental azole resistance mutation in Aspergillus fumigatus and a possible role of sexual reproduction in its emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
Van Dijk, Karin
Hagen, Ferry
Van Der Beek, Martha T.
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J.G.
Verweij, Paul E.
Debets, Alfons J.M.

May 2017

This study investigated the dynamics of Aspergillus fumigatus azoleresistant phenotypes in two compo...

Discovery of a hapE Mutation That Causes Azole Resistance in Aspergillus fumigatus through Whole Genome Sequencing and Sexual Crossing

Camps, S.M.T.
Dutilh, B.E.
Arendrup, M.C.
Rijs, A.J.M.M.
Snelders, E.
Huynen, M.A.
Verweij, P.E.
Melchers, W.J.G.

January 2012

Contains fulltext : 110931.pdf (publisher's version ) (Open Access)Azole compounds...

Molecular mechanisms of azole resistance in Aspergillus fumigatus

Camps, S.M.T.

January 2013

Contains fulltext : 112900.pdf (publisher's version ) (Open Access)Radboud Univers...

Discovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing.

Simone M T Camps
Bas E Dutilh
Maiken C Arendrup
Antonius J M M Rijs
Eveline Snelders
Martijn A Huynen
Paul E Verweij
Willem J G Melchers

Azole compounds are the primary therapy for patients with diseases caused by Aspergillus fumigatus. ...

Discovery of a hapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing. PLoS One 2012

Simone M. T. Camps
Bas E. Dutilh
Maiken C. Arendrup
Antonius J. M. M. Rijs
Eveline Snelders
Martijn A. Huynen
Paul E. Verweij
Willem J. G. Melchers

August 2016

Azole compounds are the primary therapy for patients with diseases caused by Aspergillus fumigatus. ...

Discovery of a hapE Mutation That Causes Azole Resistance in Aspergillus fumigatus through Whole Genome Sequencing and Sexual Crossing

Camps, Simone M.T.
Dutilh, Bas E.
Arendrup, Maiken C.
Rijs, Antonius J.M.M.
Snelders, Eveline
Huynen, Martijn A.
Verweij, Paul E.
Melchers, Willem J.G.

January 2012

Azole compounds are the primary therapy for patients with diseases caused by Aspergillus fumigatus. ...

Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing

Abdolrasouli, A.
Rhodes, J.
Beale, M.A.
Hagen, F.
Rogers, T.R.
Chowdhary, A.
Meis, J.F.G.M.
Armstrong-James, D.
Fisher, M.C.

January 2015

Contains fulltext : 155363.pdf (publisher's version ) (Open Access)A rapid and glo...

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

Zhang, J.
Snelders, E.
Zwaan, B.J.
Schoustra, S.E.
Meis, J.F.G.M.
Dijk, K van
Hagen, F.
Beek, M.T. van der
Kampinga, G.A.
Zoll, J.
Melchers, W.J.G.
Verweij, P.E.
Debets, A.J.

January 2017

Contains fulltext : 177560.pdf (publisher's version ) (Open Access)This study inve...

Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis.

Linden, J.W. van der
Arendrup, M.C.
Melchers, W.J.
Verweij, P.E.

January 2016

Contains fulltext : 171999.pdf (publisher's version ) (Open Access

Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing

Abdolrasouli, A.
Rhodes, J.
Beale, M.A.
Hagen, F.
Rogers, T.R.
Chowdhary, A.
Meis, J.F.G.M.
Armstrong-James, D.
Fisher, M.C.

January 2015

A rapid and global emergence of azole resistance has been observed in the pathogenic fungus Aspergil...

A novel environmental azole resistance mutation in Aspergillus fumigatus and a possible role of sexual reproduction in its emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
Dijk, Karin, van
Hagen, Ferry
Beek, Martha T., van der
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J.G.
Verweij, Paul E.
Debets, Fons

January 2017

This study investigated the dynamics of Aspergillus fumigatus azoleresistant phenotypes in two compo...

A novel environmental azole resistance mutation in Aspergillus fumigatus and a possible role of sexual reproduction in its emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
Dijk, van, Karin
Hagen, Ferry
Beek, van der, Martha T.
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J.G.
Verweij, Paul E.
Debets, Fons

January 2017

This study investigated the dynamics of Aspergillus fumigatus azoleresistant phenotypes in two compo...

Azole resistance profile of amino acid changes in Aspergillus fumigatus CYP51A based on protein homology modeling.

Snelders, E.
Karawajczyk, A.
Schaftenaar, G.
Verweij, P.E.
Melchers, W.J.G.

January 2010

Contains fulltext : 88470.pdf (publisher's version ) (Open Access)Molecular studie...

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
van Dijk, Karin
Hagen, Ferry
van der Beek, Martha T.
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J. G.
Verweij, Paul E.
Debets, Alfons J. M.

January 2017

This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two comp...

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

Zhang, J.
Snelders, E.
Zwaan, B.J.
Schoustra, S.E.
Meis, J.F.G.M.
Dijk, K van
Hagen, F.
Beek, M.T. van der
Kampinga, G.A.
Zoll, J.
Melchers, W.J.G.
Verweij, P.E.
Debets, A.J.

January 2017

This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two comp...

A novel environmental azole resistance mutation in Aspergillus fumigatus and a possible role of sexual reproduction in its emergence

Zhang, Jianhua
Snelders, Eveline
Zwaan, Bas J.
Schoustra, Sijmen E.
Meis, Jacques F.
Van Dijk, Karin
Hagen, Ferry
Van Der Beek, Martha T.
Kampinga, Greetje A.
Zoll, Jan
Melchers, Willem J.G.
Verweij, Paul E.
Debets, Alfons J.M.

May 2017

This study investigated the dynamics of Aspergillus fumigatus azoleresistant phenotypes in two compo...

Discovery of a new azole resistance mechanism in Aspergillus fumigatus through whole genome sequencing and sexual crossing.

Abstract

Extracted data

Discovery of a new azole resistance mechanism in Aspergillus fumigatus through whole genome sequencing and sexual crossing.

Abstract

Extracted data

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