Furnishing amine-functionalized metal-organic-frameworks with the β-amidoketone group by post-synthetic modification

The post-synthetic modification (PSM) of amino-functionalized MOFs to those bearing pendant β-amidoketone arms using diketene is herein reported. Three unique MOF families demonstrate the scope of this transformation, which is both atom-economical and yields high conversions. In each case crystallinity was retained, and instances of exceptional solid-state ordering were observed in the PSM products, which has allowed detailed crystallographic characterization in multiple instances