The emergence and survival of cooperation is one of the hardest problems still open in science. Several factors such as the existence of punishment, repeated interactions, topological effects and the formation of prestige may all contribute to explain the counter-intuitive prevalence of cooperation in natural and social systems. The characteristics of the interaction networks have been also signaled as an element favoring the persistence of cooperators. Here we consider the invasion dynamics of cooperative behaviors in complex topologies. The invasion of a heterogeneous network fully occupied by defectors is performed starting from nodes with a given number of connections (degree) k0. The system is then evolved within a Prisoner’s Dilemma g...