CD123 expression levels in 846 acute leukemia patients based on standardized immunophenotyping
- Bras, A.E. (Anne)
- Haas, V. (Valerie) de
- van Stigt, A. (Arthur)
- Jongen-Lavrencic, M. (Mojca)
- Beverloo, H.B. (Berna)
- Marvelde, J.G. (Jeroen) te
- Zwaan, C.M. (Michel)
- Dongen, J.J.M. (Jacques) van
- Leusen, R. (Robert) van
- Velden, V.H.J. (Vincent) van der
DOIAbstract
Background: While it is known that CD123 is normally strongly expressed on plasmacytoid dendritic cells and completely absent on nucleated red blood cells, detailed information regarding CD123 expression in acute leukemia is scarce and, if available, hard to compare due to different methodologies. Methods: CD123 expression was evaluated using standardized EuroFlow immunophenotyping in 139 pediatric AML, 316 adult AML, 193 pediatric BCP-ALL, 69 adult BCP-ALL, 101 pediatric T-A
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