First-time, mild diverticulitis: Antibiotics or watchful waiting?

Review of: Daniels L, Ünlü Ç, de Korte N, et al, for the Dutch Diverticular Disease (3D) Collaborative Study Group. Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis. Br J Surg. 2017;104:52-61.First-time, mild diverticulitis: antibiotics or watchful waiting? Don't jump to antibiotic Tx for mild, uncomplicated diverticulitis, a recent RCT says. Observation may be just as effective. Practice changer: For mild, computed tomography-proven acute diverticulitis, consider observation only instead of antibiotic therapy. Stength of recommendation: B: Based on a single randomized controlled trial.Bob Marshall, MD, MPH, MISM, FAAFP; Shailendra Prasad, MBBS, MPH; Mary Alice Noel, MD; Jeffrey Burket, MD, FAAFP; Michael Arnold, DO, FAAFP; Benjamin Arthur, MD; Nick Bennett, DO; Ashley Smith, MD ; Madigan Family Medicine Residency, Gig Harbor, Wash (Drs. Marshall, Noel, Burket, Arnold, Arthur, Bennett, Smith); University of Minnesota Family Medicine and Community Health, Minneapolis (Dr. Prasad