Hydrazine-induced liver toxicity is enhanced by glutathione depletion but is not mediated by oxidative stress in HepG2 cells.

Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects

Ntamo Y.
Ziqubu K.
Chellan N.
Nkambule B. B.
Nyambuya T. M.
Mazibuko-Mbeje S. E.
Gabuza K. B.
Marcheggiani F.
Tiano L.
Dludla P. V.

January 2021

Oxidative stress is a key pathological feature implicated in both acute and chronic liver diseases, ...

Oxidative Stress in Liver Disease

Singh, L
Majhi, S
Pabreja, K
Negi, P
Goyal, R
Gupta, G
Chellappan, DK
Dua, K

May 2021

Liver, being the second largest organ, maintains homeostasis by undergoing a number of risk factors ...

CYTOPROTECTIVE EFFECTS OF TAURINE AGAINST TOXICITY INDUCED BY ISONIAZID AND HYDRAZINE IN ISOLATED RAT HEPATOCYTES

Reza Heidari
Hossein Babaei
Mohammad Ali Eghbal
Arh Hig
Rada Toksikol

January 2012

Isoniazid is one of the most commonly used drugs to treat tuberculosis. Its administration is associ...

Isoniazid and its toxic metabolite hydrazine induce in vitro pyrazinamide toxicity.

Tostmann, A.
Boeree, M.J.
Peters, W.H.M.
Roelofs, H.M.J.
Aarnoutse, R.E.
Ven, A.J.A.M. van der
Dekhuijzen, P.N.R.

January 2008

Contains fulltext : 69581.pdf (publisher's version ) (Closed access)Antituberculos...

The role of acetylation in the hepatotoxicity of hydrazine

Richards, Victoria Elizabeth
Richards, Victoria Elizabeth

January 2004

Isoniazid (INH) is an antimicrobial used around the world in the treatment and chemoprophylaxis of t...

Possible role of free radical intermediates in hepatotoxicity of hydrazines derivatives

ALBANO E
GORIAGATTI L
CLOT P
IANNONE, Anna
TOMASI, Aldo

January 1993

Hydrazine derivatives constitute a wide group of compounds and have found application in industry, a...

Occupational Medicine 2007;57:535–537

Case Report
Yung Hsiang Kao
C. H. Chong
W. T. Ng
D. Lim

January 2007

Abstract Hydrazine is a hazardous chemical commonly used as a reactant in rocket and jet fuel cells....

Effect of hydrazine upon vitamin B12-dependent methionine synthase activity and the sulphur amino acid pathway in isolated rat hepatocytes

Kenyon, Susan H.
Waterfield, Catherine J.
Asker, Daniel S.
Kudo, Mariko
Moss, David W.
Bates, Timothy E.
Nicolaou, Anna
Gibbons, William A.
Timbrell, John A.

June 1999

The effect of the industrial chemical, hydrazine (4-12 mM), on methionine synthase (EC 2.1.1.13) act...

Hepatic Gene Expression and Lipid Homeostasis in C57Bl/6 Mice Exposed to Hydrazine or Acetylhydrazine

Victoria E. Richards
Binh Chau
Y White
Charlene A. Mcqueen

January 2004

Hydrazine (HD) and acetylhydrazine (AcHD) are metabolites of the antituberculosis drug isoniazid (IN...

The Effects of Cyp2e1 on Hepatic Gene Expression in 129/Sv-Cyp2e1^tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine

Lindgren, Kristjon
Seng, Dana

January 2007

Class of 2007 AbstractObjectives: To characterize the difference in hepatic gene expression between ...

Mechanisms of Drug-induced Oxidative Stress in the Hepatocyte Inflammation Model

Tafazoli, Shahrzad

February 2009

Drug induced idiosyncratic agranulocytosis has been attributed to oxidation by hypochlorite formed b...

Xanthine oxidase inhibition by allopurinol increases in vitro pyrazinamide-induced hepatotoxicity in HepG2 cells.

Tostmann, A.
Aarnoutse, R.E.
Peters, W.H.M.
Richard, P.N.
Boeree, M.J.

January 2010

Contains fulltext : 87446.pdf (publisher's version ) (Open Access)Despite the impo...

THE ROLE OF VITAMIN Be IN THE TOXICITY OF HYDRAZINES*

Herbert H. Cornish

October 2016

Within recent years hydrazine and the methyl substituted hydrazines have come into considerable use ...

Research Report 1: The role of glutathione in idiosyncratic and non-idiosyncratic drug induced liver injury

Starokozhko, V.

January 2013

Introduction: The probability of idiosyncratic drug-induced liver injury (IDILI) occurrence is defin...

Glutathione in the treatment of liver diseases: insights from clinical practice

Sacco, Rodolfo
Eggenhoffner, Roberto
Giacomelli, Luca

January 2016

Liver diseases markedly contribute to the global burden of mortality and morbidity. The pathogenesis...

Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects

Ntamo Y.
Ziqubu K.
Chellan N.
Nkambule B. B.
Nyambuya T. M.
Mazibuko-Mbeje S. E.
Gabuza K. B.
Marcheggiani F.
Tiano L.
Dludla P. V.

January 2021

Oxidative stress is a key pathological feature implicated in both acute and chronic liver diseases, ...

Oxidative Stress in Liver Disease

Singh, L
Majhi, S
Pabreja, K
Negi, P
Goyal, R
Gupta, G
Chellappan, DK
Dua, K

May 2021

Liver, being the second largest organ, maintains homeostasis by undergoing a number of risk factors ...

CYTOPROTECTIVE EFFECTS OF TAURINE AGAINST TOXICITY INDUCED BY ISONIAZID AND HYDRAZINE IN ISOLATED RAT HEPATOCYTES

Reza Heidari
Hossein Babaei
Mohammad Ali Eghbal
Arh Hig
Rada Toksikol

January 2012

Isoniazid is one of the most commonly used drugs to treat tuberculosis. Its administration is associ...

Isoniazid and its toxic metabolite hydrazine induce in vitro pyrazinamide toxicity.

Tostmann, A.
Boeree, M.J.
Peters, W.H.M.
Roelofs, H.M.J.
Aarnoutse, R.E.
Ven, A.J.A.M. van der
Dekhuijzen, P.N.R.

January 2008

Contains fulltext : 69581.pdf (publisher's version ) (Closed access)Antituberculos...

The role of acetylation in the hepatotoxicity of hydrazine

Richards, Victoria Elizabeth
Richards, Victoria Elizabeth

January 2004

Isoniazid (INH) is an antimicrobial used around the world in the treatment and chemoprophylaxis of t...

Possible role of free radical intermediates in hepatotoxicity of hydrazines derivatives

ALBANO E
GORIAGATTI L
CLOT P
IANNONE, Anna
TOMASI, Aldo

January 1993

Hydrazine derivatives constitute a wide group of compounds and have found application in industry, a...

Occupational Medicine 2007;57:535–537

Case Report
Yung Hsiang Kao
C. H. Chong
W. T. Ng
D. Lim

January 2007

Abstract Hydrazine is a hazardous chemical commonly used as a reactant in rocket and jet fuel cells....

Effect of hydrazine upon vitamin B12-dependent methionine synthase activity and the sulphur amino acid pathway in isolated rat hepatocytes

Kenyon, Susan H.
Waterfield, Catherine J.
Asker, Daniel S.
Kudo, Mariko
Moss, David W.
Bates, Timothy E.
Nicolaou, Anna
Gibbons, William A.
Timbrell, John A.

June 1999

The effect of the industrial chemical, hydrazine (4-12 mM), on methionine synthase (EC 2.1.1.13) act...

Hepatic Gene Expression and Lipid Homeostasis in C57Bl/6 Mice Exposed to Hydrazine or Acetylhydrazine

Victoria E. Richards
Binh Chau
Y White
Charlene A. Mcqueen

January 2004

Hydrazine (HD) and acetylhydrazine (AcHD) are metabolites of the antituberculosis drug isoniazid (IN...

The Effects of Cyp2e1 on Hepatic Gene Expression in 129/Sv-Cyp2e1^tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine

Lindgren, Kristjon
Seng, Dana

January 2007

Class of 2007 AbstractObjectives: To characterize the difference in hepatic gene expression between ...

Mechanisms of Drug-induced Oxidative Stress in the Hepatocyte Inflammation Model

Tafazoli, Shahrzad

February 2009

Drug induced idiosyncratic agranulocytosis has been attributed to oxidation by hypochlorite formed b...

Xanthine oxidase inhibition by allopurinol increases in vitro pyrazinamide-induced hepatotoxicity in HepG2 cells.

Tostmann, A.
Aarnoutse, R.E.
Peters, W.H.M.
Richard, P.N.
Boeree, M.J.

January 2010

Contains fulltext : 87446.pdf (publisher's version ) (Open Access)Despite the impo...

THE ROLE OF VITAMIN Be IN THE TOXICITY OF HYDRAZINES*

Herbert H. Cornish

October 2016

Within recent years hydrazine and the methyl substituted hydrazines have come into considerable use ...

Research Report 1: The role of glutathione in idiosyncratic and non-idiosyncratic drug induced liver injury

Starokozhko, V.

January 2013

Introduction: The probability of idiosyncratic drug-induced liver injury (IDILI) occurrence is defin...

Glutathione in the treatment of liver diseases: insights from clinical practice

Sacco, Rodolfo
Eggenhoffner, Roberto
Giacomelli, Luca

January 2016

Liver diseases markedly contribute to the global burden of mortality and morbidity. The pathogenesis...

Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects

Ntamo Y.
Ziqubu K.
Chellan N.
Nkambule B. B.
Nyambuya T. M.
Mazibuko-Mbeje S. E.
Gabuza K. B.
Marcheggiani F.
Tiano L.
Dludla P. V.

January 2021

Oxidative stress is a key pathological feature implicated in both acute and chronic liver diseases, ...

Oxidative Stress in Liver Disease

Singh, L
Majhi, S
Pabreja, K
Negi, P
Goyal, R
Gupta, G
Chellappan, DK
Dua, K

May 2021

Liver, being the second largest organ, maintains homeostasis by undergoing a number of risk factors ...

CYTOPROTECTIVE EFFECTS OF TAURINE AGAINST TOXICITY INDUCED BY ISONIAZID AND HYDRAZINE IN ISOLATED RAT HEPATOCYTES

Reza Heidari
Hossein Babaei
Mohammad Ali Eghbal
Arh Hig
Rada Toksikol

January 2012

Isoniazid is one of the most commonly used drugs to treat tuberculosis. Its administration is associ...

Hydrazine-induced liver toxicity is enhanced by glutathione depletion but is not mediated by oxidative stress in HepG2 cells.

Abstract

Extracted data

Hydrazine-induced liver toxicity is enhanced by glutathione depletion but is not mediated by oxidative stress in HepG2 cells.

Abstract

Extracted data

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