International audienceThe Earth's solid inner core exhibits a global seismic anisotropy of several percents. It results from a coherent alignment of anisotropic Fe alloy crystals through the inner-core history that can be sampled by present-day seismic observations. By combining self-consistent polycrystal plasticity, inner-core formation models, Monte-Carlo search for elastic moduli, and simulations of seismic measurements, we introduce a multiscale model that can reproduce a global seismic anisotropy of several percents aligned with the Earth's rotation axis. Conditions for a successful model are an hexagonal close packed structure for the inner-core Fe alloy, plastic deformation by pyramidal ⟨c + a⟩ slip, and large-scale flow induced by ...