The results of this study indicate that exogenously-generated oxy-radicals produce relaxation, contraction or contraction/relaxation of rat ileum depending upon the generating system. Xanthine (X) plus xanthine oxidase (XO) produced relaxation of ileum. The relaxation was attenuated by the hydroxyl radical scavengers mannitol and dimethylthiourea (DMTU); and the singlet oxygen scavenger, histidine, supporting the idea that the hydroxyl radical (.OH) and singlet oxygen are involved in X/XO-induced relaxation of ileum. Deferoxamine, an iron chelator, reduced the relaxation of the ileum, indicating that .OH mediates the X/XO-induced relaxation of ileum. Xanthine/xanthine oxidase-induced relaxation is partly mediated through cyclooxygenase meta...
Recent evidence indicates that hypoxia enhances the generation of oxidants. Little is known about th...
This investigation aimed to determine whether contractile dysfunction of the myocardium could be pro...
tive oxygen species on AH/type 2 myenteric neurons in guinea pig distal colon. Am J Physiol Gastroin...
The results of this study indicate that exogenously-generated oxy-radicals produce relaxation, contr...
The major objective of the present study was to characterize the effects of oxidants generated b xan...
Experiments were designed to determine the role of oxygen-derived free radicals in modulating contra...
Literature data suggest that the inflamed intestine may be subjected to a considerable oxidative str...
To determine if oxygen-derived free radicals are mediators of endothelium-dependent contractions to ...
To determine if oxygen-derived free radicals are mediators of endothelium-dependent contrac-tions to...
Muscle vasodilatation evoked by systemic hypoxia is adenosine mediated and nitric oxide (NO) depende...
In vivo and in vitro studies on numerous types of blood vessels obtained from a variety of vascular ...
1. Experiments were designed to investigate whether or not oxygen-derived free radicals mediate endo...
Recent evidence indicates that hypoxia enhances the generation of oxidants. Little is known about th...
This investigation aimed to determine whether contractile dysfunction of the myocardium could be pro...
Because oxidative stress is a component of gastrointestinal injury, we investigated the effect of H(...
Recent evidence indicates that hypoxia enhances the generation of oxidants. Little is known about th...
This investigation aimed to determine whether contractile dysfunction of the myocardium could be pro...
tive oxygen species on AH/type 2 myenteric neurons in guinea pig distal colon. Am J Physiol Gastroin...
The results of this study indicate that exogenously-generated oxy-radicals produce relaxation, contr...
The major objective of the present study was to characterize the effects of oxidants generated b xan...
Experiments were designed to determine the role of oxygen-derived free radicals in modulating contra...
Literature data suggest that the inflamed intestine may be subjected to a considerable oxidative str...
To determine if oxygen-derived free radicals are mediators of endothelium-dependent contractions to ...
To determine if oxygen-derived free radicals are mediators of endothelium-dependent contrac-tions to...
Muscle vasodilatation evoked by systemic hypoxia is adenosine mediated and nitric oxide (NO) depende...
In vivo and in vitro studies on numerous types of blood vessels obtained from a variety of vascular ...
1. Experiments were designed to investigate whether or not oxygen-derived free radicals mediate endo...
Recent evidence indicates that hypoxia enhances the generation of oxidants. Little is known about th...
This investigation aimed to determine whether contractile dysfunction of the myocardium could be pro...
Because oxidative stress is a component of gastrointestinal injury, we investigated the effect of H(...
Recent evidence indicates that hypoxia enhances the generation of oxidants. Little is known about th...
This investigation aimed to determine whether contractile dysfunction of the myocardium could be pro...
tive oxygen species on AH/type 2 myenteric neurons in guinea pig distal colon. Am J Physiol Gastroin...