Protected DHA units, known as dioxanones, are interesting compound which can be used as the building blocks for synthesis of polyoxygenated natural products. The direct aldol reaction is employed for converting of those inexpensive starting materials into enantioenriched products of complexed structures. The stereocontrol in the first aldol reaction is achieved by using organocatalysis. Second aldol reaction is conducted by lithium enolate chemistry leading to anti–cis–anti aldols as a major isomer. On the other hand boron chemistry provides anti–trans–anti products. This strategy is used for synthesis of higher sugars
[spa] Los compuestos polihidroxilados, como carbohidratos y sus derivados son moléculas de gran impo...
The organocatalytic aldol reaction of tropinone with benzaldehyde using (S)-5-pyrrolidin-2-yl-1H-tet...
Polyhydroxylated compounds are building blocks for the synthesis of carbohydrates and other natural ...
Protected DHA units, known as dioxanones, are interesting compound which can be used as the building...
Dioxanones (1) are ketal- or acetal protected forms of 1,3-dihydroxyacetone (DHA). The thesis presen...
A straightforward synthetic pathway allowing the access to anti or syn 2-amino-1,3-diol scaffolds is...
International audienceA straightforward synthetic pathway allowing the access to anti or syn 2-amino...
Two complementary classes of chiral boron enolates for adaptation to aldol additions to resin-bound ...
Reported herein is the development of the highly α-regio- and diastereoselective aldol reactions of ...
[Structure: see text] For the first time, unmodified ynones were used in organocatalytic asymmetric ...
Polyhydroxylated compounds are building blocks for the synthesis of carbohydrates and other natural ...
The first enantioselective direct aldol addition of N-Boc-oxindoles to polymeric ethyl glyoxylate is...
Butane-2,3-diacetal (BDA) desymmetrised glycolic acid building block 1 undergoes highly diastereosel...
1-Amino-3-hydroxyacetone (AHA, 1) is the deoxyamino-derivative of 1,3-dihydroxyacetone (DHA, 2). Nat...
Carbon-carbon bond formation is one of the most challenging reactions in synthetic organic chemistry...
[spa] Los compuestos polihidroxilados, como carbohidratos y sus derivados son moléculas de gran impo...
The organocatalytic aldol reaction of tropinone with benzaldehyde using (S)-5-pyrrolidin-2-yl-1H-tet...
Polyhydroxylated compounds are building blocks for the synthesis of carbohydrates and other natural ...
Protected DHA units, known as dioxanones, are interesting compound which can be used as the building...
Dioxanones (1) are ketal- or acetal protected forms of 1,3-dihydroxyacetone (DHA). The thesis presen...
A straightforward synthetic pathway allowing the access to anti or syn 2-amino-1,3-diol scaffolds is...
International audienceA straightforward synthetic pathway allowing the access to anti or syn 2-amino...
Two complementary classes of chiral boron enolates for adaptation to aldol additions to resin-bound ...
Reported herein is the development of the highly α-regio- and diastereoselective aldol reactions of ...
[Structure: see text] For the first time, unmodified ynones were used in organocatalytic asymmetric ...
Polyhydroxylated compounds are building blocks for the synthesis of carbohydrates and other natural ...
The first enantioselective direct aldol addition of N-Boc-oxindoles to polymeric ethyl glyoxylate is...
Butane-2,3-diacetal (BDA) desymmetrised glycolic acid building block 1 undergoes highly diastereosel...
1-Amino-3-hydroxyacetone (AHA, 1) is the deoxyamino-derivative of 1,3-dihydroxyacetone (DHA, 2). Nat...
Carbon-carbon bond formation is one of the most challenging reactions in synthetic organic chemistry...
[spa] Los compuestos polihidroxilados, como carbohidratos y sus derivados son moléculas de gran impo...
The organocatalytic aldol reaction of tropinone with benzaldehyde using (S)-5-pyrrolidin-2-yl-1H-tet...
Polyhydroxylated compounds are building blocks for the synthesis of carbohydrates and other natural ...