In this doctoral work, Ingvild Gudim and co-workers have studied a network of proteins that transfer electrons to each other. They have shown that even if these proteins are structurally similar and have the same function, they still transfer electrons with hugely different efficiencies. This knowledge is valuable in industrial biotechnology, where proteins are often used to catalyse reactions, and finding the most efficient protein for this is important. This particular protein network is used in bacteria to activate an indispensable protein – ribonucleotide reductase – the only protein that produces DNA building blocks. This protein exists in both bacteria and humans, but in slightly different forms. Gudim and colleagues have established ...
Oxidoreductases are a diverse class of enzymes defined by their chemical role of transferring electr...
Flavodoxins are small electron transport proteins that are involved in a myriad of photosynthetic an...
Primitive proteins are proposed to have utilized organic cofactors more frequently than transition m...
Flavodoxins (Flds) are small, bacterial proteins that transfer electrons to various redox enzymes. F...
Ribonucleotide reductase (RNR) catalyses the reduction of the four ribonucleotides to their correspo...
Cytochromes P450 are diverse group of heme enzymes found in most species on Earth. In humans they ar...
An unusual yet strongly conserved flavoprotein reductase in bacteria nd mammals THE TRANSFER of redu...
Elevation in the plasma level of homocysteine, a sulfur-containing amino acid, has been identified a...
Ferredoxins are iron-sulfur proteins that transfer electrons in different cellular processes. In Bac...
The recent determination of the amino acid sequences of the Bacillus megaterium cytochrome P-450 and...
Ferredoxin-NADP+ reductase (FNR, EC 1.18.1.2) is a functional class of proteins that catalyzes the t...
Redox reactions are central to biochemistry and are both controlled by and induce protein structural...
Fusobacterium nucleatum, a Gram-negative oral bacterium, is linked to periodontal disease, colorecta...
Antimicrobial drug resistance in pathogens is an increasing human health problem. The rapid loss of ...
protein interactions, X-ray structure Electron transfer (ET) reactions in systems involving proteins...
Oxidoreductases are a diverse class of enzymes defined by their chemical role of transferring electr...
Flavodoxins are small electron transport proteins that are involved in a myriad of photosynthetic an...
Primitive proteins are proposed to have utilized organic cofactors more frequently than transition m...
Flavodoxins (Flds) are small, bacterial proteins that transfer electrons to various redox enzymes. F...
Ribonucleotide reductase (RNR) catalyses the reduction of the four ribonucleotides to their correspo...
Cytochromes P450 are diverse group of heme enzymes found in most species on Earth. In humans they ar...
An unusual yet strongly conserved flavoprotein reductase in bacteria nd mammals THE TRANSFER of redu...
Elevation in the plasma level of homocysteine, a sulfur-containing amino acid, has been identified a...
Ferredoxins are iron-sulfur proteins that transfer electrons in different cellular processes. In Bac...
The recent determination of the amino acid sequences of the Bacillus megaterium cytochrome P-450 and...
Ferredoxin-NADP+ reductase (FNR, EC 1.18.1.2) is a functional class of proteins that catalyzes the t...
Redox reactions are central to biochemistry and are both controlled by and induce protein structural...
Fusobacterium nucleatum, a Gram-negative oral bacterium, is linked to periodontal disease, colorecta...
Antimicrobial drug resistance in pathogens is an increasing human health problem. The rapid loss of ...
protein interactions, X-ray structure Electron transfer (ET) reactions in systems involving proteins...
Oxidoreductases are a diverse class of enzymes defined by their chemical role of transferring electr...
Flavodoxins are small electron transport proteins that are involved in a myriad of photosynthetic an...
Primitive proteins are proposed to have utilized organic cofactors more frequently than transition m...