Infectious diseases represent an urgent public health problem globally. Particularly healthcare-associated infections are often complicated by antibiotic resistance and presence of recalcitrant microbial biofilms. On the hunt for effective antibiotics with novel mechanisms of action (MOA), researchers look into largely unexplored natural environments with high biodiversity like the oceans, rich in unique natural compounds. In this project, we evaluated the antibacterial potential of a library of synthetic marine natural product mimics (MNPMs) in collaboration with a PhD project in chemistry, both parts of MabCent CRI, Centre for Research-based Innovation on Marine Bioactivities and Drug Discovery. The MNPM library that included 52 compounds...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
Infectious diseases have been a problem for humans since the beginning of human existence. The “gold...
The ability to form a biofilm, bacterial communities able to grow on surfaces and surrounded by an...
Methicillin-resistant Staphylococcus aureus (MRSA) is a major human pathogen associated with a varie...
The marine environment is a rich source of chemically diverse, biologically active natural products,...
Bacterial biofilms are highly organized surface-associated communities of bacteria encased within an...
Antibiotics have revolutionised medicine in many aspects, and their discovery is considered a turnin...
Natural products from the unique environments of sea water and oceans represent a largely unfamiliar...
Bacterial biofilms are highly organized surface-associated communities of bacteria encased within an...
Bacterial biofilms are highly organized surface-associated communities of bacteria encased within an...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
Infectious diseases have been a problem for humans since the beginning of human existence. The “gold...
The ability to form a biofilm, bacterial communities able to grow on surfaces and surrounded by an...
Methicillin-resistant Staphylococcus aureus (MRSA) is a major human pathogen associated with a varie...
The marine environment is a rich source of chemically diverse, biologically active natural products,...
Bacterial biofilms are highly organized surface-associated communities of bacteria encased within an...
Antibiotics have revolutionised medicine in many aspects, and their discovery is considered a turnin...
Natural products from the unique environments of sea water and oceans represent a largely unfamiliar...
Bacterial biofilms are highly organized surface-associated communities of bacteria encased within an...
Bacterial biofilms are highly organized surface-associated communities of bacteria encased within an...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
International audienceIn the marine environment, most solid surfaces are covered by microbial biofil...
Infectious diseases have been a problem for humans since the beginning of human existence. The “gold...
The ability to form a biofilm, bacterial communities able to grow on surfaces and surrounded by an...