Add to ORKGWe proposed 5 main objetives in this doctoral thesis: 1. To determine changes in miRNA expression in human intestinal epithelial cells, depending on the stage of cell differentiation and inflammation. 2. To study miR-146a expression in three animal models of colitis, that differ in the involvement of the intestinal mucosal barrier and, accordingly, in the level of contact with the intestinal microbiota. 3. To study the effect of bacterial antigens and cytokines on the expression of miR-146a using IEC lines. 4. To confirm the hypothesis that miR-146a may contribute to prevent overstimulation of the immune response. 5. To study the effect of bacterial antigens and cytokines on the expression of miR-146a using organoids from mouse sm...
BACKGROUND: Evidence suggests the central role of tumor necrosis factor (TNF)-alpha in the pathomech...
<p>(A) HCT-116 and (B) Caco2 cells after incubation with pro-inflammatory cytokines. Relative microR...
(A) INS1 cells were exposed to IL-1β (160 pg/ml) for 6 h, 12 h and 24 h. The expression of miR-146a-...
We proposed 5 main objetives in this doctoral thesis: 1. To determine changes in miRNA expression ...
Regulation of miR-146a abundance and its role in intestinal inflammation and particularly in intesti...
Accumulating evidence indicates that microRNA-146a (miR-146a), a well-known anti-inflammatory miRNA,...
<p>A, miR-138 was significantly downregulated in colitis. B, miR-145 was significantly downregulated...
MicroRNAs (miRNAs) are non-coding RNA sequences involved in post-transcriptional gene regulation of ...
The potential immunomodulatory role of microRNAs in small intestine of patients with acute watery di...
MicroRNAs (miRNAs) are epigenetically involved in regulating gene expression. They may be of importa...
The dissertation entitled ‘cross-talk between microbiota and immune responses in inflammatory bowel ...
The potential immunomodulatory role of microRNAs in small intestine of patients with acute watery di...
MicroRNAs (miRNAs) are regulatory molecules able to influence all aspects of the biology of a cell....
The gut microbiota and microRNAs play important roles in the defense against infection. However, the...
dissertationMicroRNAs (miRNAs) are small, noncoding RNA regulators of gene expression that have many...
BACKGROUND: Evidence suggests the central role of tumor necrosis factor (TNF)-alpha in the pathomech...
<p>(A) HCT-116 and (B) Caco2 cells after incubation with pro-inflammatory cytokines. Relative microR...
(A) INS1 cells were exposed to IL-1β (160 pg/ml) for 6 h, 12 h and 24 h. The expression of miR-146a-...
We proposed 5 main objetives in this doctoral thesis: 1. To determine changes in miRNA expression ...
Regulation of miR-146a abundance and its role in intestinal inflammation and particularly in intesti...
Accumulating evidence indicates that microRNA-146a (miR-146a), a well-known anti-inflammatory miRNA,...
<p>A, miR-138 was significantly downregulated in colitis. B, miR-145 was significantly downregulated...
MicroRNAs (miRNAs) are non-coding RNA sequences involved in post-transcriptional gene regulation of ...
The potential immunomodulatory role of microRNAs in small intestine of patients with acute watery di...
MicroRNAs (miRNAs) are epigenetically involved in regulating gene expression. They may be of importa...
The dissertation entitled ‘cross-talk between microbiota and immune responses in inflammatory bowel ...
The potential immunomodulatory role of microRNAs in small intestine of patients with acute watery di...
MicroRNAs (miRNAs) are regulatory molecules able to influence all aspects of the biology of a cell....
The gut microbiota and microRNAs play important roles in the defense against infection. However, the...
dissertationMicroRNAs (miRNAs) are small, noncoding RNA regulators of gene expression that have many...
BACKGROUND: Evidence suggests the central role of tumor necrosis factor (TNF)-alpha in the pathomech...
<p>(A) HCT-116 and (B) Caco2 cells after incubation with pro-inflammatory cytokines. Relative microR...
(A) INS1 cells were exposed to IL-1β (160 pg/ml) for 6 h, 12 h and 24 h. The expression of miR-146a-...