Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder.
- Zhou, K.
- Dempfle, A.
- Arcos-Burgos, M.
- Bakker, S.C.
- Banaschewski, T.
- Biederman, J.
- Buitelaar, J.K.
- Castellanos, F.X.
- Doyle, A.
- Ebstein, R.P.
- Ekholm, J.
- Forabosco, P.
- Franke, B.
- Freitag, C.
- Friedel, S.
- Gill, M.
- Hebebrand, J.
- Hinney, A.
- Jacob, C.
- Lesch, K.P.
- Loo, S.K.
- Lopera, F.
- McCracken, J.T.
- McGough, J.J.
- Meyer, J.
- Mick, E.
- Miranda, A.
- Muenke, M.
- Mulas, F.
- Nelson, S.F.
- Nguyen, T.T.
- Oades, R.D.
- Ogdie, M.N.
- Palacio, J.D.
- Pineda, D.
- Reif, A.
- Renner, T.J.
- Roeyers, H.
- Romanos, M.
- Rothenberger, A.
- Schafer, H.
- Sergeant, J.A.
- Sinke, R.J.
- Smalley, S.L.
- Sonuga-Barke, E.J.S.
- Steinhausen, H.C.
- Meulen, E. van der
- Walitza, S.
- Warnke, A.
- Lewis, C.M.
- Faraone, S.V.
- Asherson, P.
DOIAbstract
Contains fulltext : 69243.pdf (publisher's version ) (Closed access)Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gathered the results from all seven of the ADHD linkage scans and performed a Genome Scan Meta Analysis (GSMA) to identify the genomic region with most consistent linkage evidence across the studies. Genome-wide significant linkage (P(SR) = 0.00034, P(OR) = 0.04) was id...
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