Renal cell carcinoma(RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses. The current study evaluated 843 RCC from the three major histologic subtypes, including 488 clear cell RCC, 274 papillary RCC, and 81 chromophobe RCC. Comprehensive genomic and phenotypic analysis of the RCC subtypes reveals distinctive features of each subtype that provide the foundation for the development of subtype-specific therapeutic and management strategies for patients affected with these cancers. Somatic alteration of BAP1, PBRM1, and PTEN and altered metabolic pathways correlated with subtype-specific decreased survival, while CDKN2A alteration, increased DNA hy...
On the basis of multidimensional and comprehensive molecular characterization (including DNA methaly...
SummaryOn the basis of multidimensional and comprehensive molecular characterization (including DNA ...
Abstract Background Renal cell carcinoma (RCC) account for over 80% of renal malignancies. The most ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
© 2018 Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancer...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma(RCC) is not a single disease, but several histologically defined cancers with d...
On the basis of multidimensional and comprehensive molecular characterization (including DNA methaly...
SummaryOn the basis of multidimensional and comprehensive molecular characterization (including DNA ...
Abstract Background Renal cell carcinoma (RCC) account for over 80% of renal malignancies. The most ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
© 2018 Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancer...
Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with ...
Renal cell carcinoma(RCC) is not a single disease, but several histologically defined cancers with d...
On the basis of multidimensional and comprehensive molecular characterization (including DNA methaly...
SummaryOn the basis of multidimensional and comprehensive molecular characterization (including DNA ...
Abstract Background Renal cell carcinoma (RCC) account for over 80% of renal malignancies. The most ...