Mitochondria-derived signals are associated with NLRP3 inflammasome activation. A recent study in Nature by Zhong et al. shows that inflammasome priming drives new mitochondrial DNA synthesis, and proposes this to be a prerequisite for NLRP3 inflammasome signaling
A current paradigm proposes that mitochondrial damage is a critical determinant of NLRP3 inflammasom...
Despite the fact that deregulated NLRP3 inflammasome activation contributes to the pathogenesis of c...
A current paradigm proposes that mitochondrial damage is a critical determinant of NLRP3 inflammasom...
Dysregulated NLRP3 inflammasome activity results in uncontrolled inflammation, which underlies many ...
Dysregulated NLRP3 inflammasome activity results in uncontrolled inflammation, which underlies many ...
The NLRP3 inflammasome is assembled and activated in certain types of myeloid cells upon sensing mic...
Danger signals released by damaged organelles can promote inflammation. In this issue of Immunity, S...
Danger signals released by damaged organelles can promote inflammation. In this issue of Immunity, S...
Danger signals released by damaged organelles can promote inflammation. In this issue of Immunity, S...
We report that in the presence of signal 1 (NF-κB), the NLRP3 inflammasome was activated by mitochon...
We report that in the presence of signal 1 (NF-kappaB), the NLRP3 inflammasome was activated by mito...
SummaryWe report that in the presence of signal 1 (NF-κB), the NLRP3 inflammasome was activated by m...
Inflammasomes are multimeric protein complexes that induce the cleavage and release of bioactive IL-...
The nod-like receptor protein 3 (NLRP3) inflammasome drives inflammation in response to mitochondria...
SummaryWe report that in the presence of signal 1 (NF-κB), the NLRP3 inflammasome was activated by m...
A current paradigm proposes that mitochondrial damage is a critical determinant of NLRP3 inflammasom...
Despite the fact that deregulated NLRP3 inflammasome activation contributes to the pathogenesis of c...
A current paradigm proposes that mitochondrial damage is a critical determinant of NLRP3 inflammasom...
Dysregulated NLRP3 inflammasome activity results in uncontrolled inflammation, which underlies many ...
Dysregulated NLRP3 inflammasome activity results in uncontrolled inflammation, which underlies many ...
The NLRP3 inflammasome is assembled and activated in certain types of myeloid cells upon sensing mic...
Danger signals released by damaged organelles can promote inflammation. In this issue of Immunity, S...
Danger signals released by damaged organelles can promote inflammation. In this issue of Immunity, S...
Danger signals released by damaged organelles can promote inflammation. In this issue of Immunity, S...
We report that in the presence of signal 1 (NF-κB), the NLRP3 inflammasome was activated by mitochon...
We report that in the presence of signal 1 (NF-kappaB), the NLRP3 inflammasome was activated by mito...
SummaryWe report that in the presence of signal 1 (NF-κB), the NLRP3 inflammasome was activated by m...
Inflammasomes are multimeric protein complexes that induce the cleavage and release of bioactive IL-...
The nod-like receptor protein 3 (NLRP3) inflammasome drives inflammation in response to mitochondria...
SummaryWe report that in the presence of signal 1 (NF-κB), the NLRP3 inflammasome was activated by m...
A current paradigm proposes that mitochondrial damage is a critical determinant of NLRP3 inflammasom...
Despite the fact that deregulated NLRP3 inflammasome activation contributes to the pathogenesis of c...
A current paradigm proposes that mitochondrial damage is a critical determinant of NLRP3 inflammasom...