Clinical Applications of Angiographic Optical Coherence Tomography

Byers, Robert

Publication date

March 2018

Publisher

University of Sheffield Conference Proceedings

Abstract

Angiographic optical coherence tomography (OCTA) has rapidly found utility within many facets of medical research. Here OCTA algorithms are enabled on a commercial OCT system and verified through correlation with intra-vital light microscopy (IVM). While the vast majority of vessels were accurately measured, smaller vessels (<30µm) have a tendency to appear dilated in comparison to IVM. The technique was also expanded upon to facilitate the imaging of subcutaneous murine fibrosarcoma tumours, negating the requirement for an intra-vital window. It was found that vessel measurement sensitivity was sufficiently high such that the morphologies of vessels within tumours expressing unique vascular endothelial growth factor (VEGF) isoforms could b...

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Clinical Applications of Angiographic Optical Coherence Tomography

Abstract

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Clinical Applications of Angiographic Optical Coherence Tomography

Abstract

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