Mechanisms involved in establishing the organization and numbers of fibres in a muscle are not completely understood. During Drosophila indirect flight muscle (IFM) formation, muscle growth is achieved by both incorporating hundreds of nuclei, and hypertrophy. As a result, IFMs provide a good model with which to understand the mechanisms that govern overall muscle organization and growth. We present a detailed analysis of the organization of dorsal longitudinal muscles (DLMs), a subset of the IFMs. We show that each DLM is similar to a vertebrate fascicle and consists of multiple muscle fibres. However, increased fascicle size does not necessarily change the number of constituent fibres, but does increase the number of myofibrils packed wit...
Myoblast fusion constitutes a fundamental aspect of muscle fiber growth, underlying the formation of...
Muscle development is a multistep process which includes myoblast diversification, proliferation, mi...
Muscle development is a multistep process which includes myoblast diversification, proliferation, mi...
Muscle fibers are multinucleated cells that arise during embryogenesis through the fusion of mononuc...
Muscle fibers are multinucleated cells that arise during embryogenesis through the fusion of mononuc...
International audienceComplex animals build specialised muscles to match specific biomechanical and ...
International audienceComplex animals build specialised muscles to match specific biomechanical and ...
The flight muscle myofibril is a precisely assembled cytoskeletal network of contractileproteins tha...
Background: Higher animals generate an elaborate muscle-tendon network to perform their movements. T...
Background: Higher animals generate an elaborate muscle-tendon network to perform their movements. T...
Complex animals build specialised muscle to match specific biomechanical and energetic needs. Hence,...
AbstractFormation of the Drosophila larval body wall muscles requires the specification, coordinated...
Pattern formation in muscle development is often mediated by special cells called muscle organizers....
AbstractDuring insect myogenesis, myoblasts are organized into a pre-pattern by specialized organize...
Mitochondrial biogenesis and morphological changes are associated with tissue-specific functional de...
Myoblast fusion constitutes a fundamental aspect of muscle fiber growth, underlying the formation of...
Muscle development is a multistep process which includes myoblast diversification, proliferation, mi...
Muscle development is a multistep process which includes myoblast diversification, proliferation, mi...
Muscle fibers are multinucleated cells that arise during embryogenesis through the fusion of mononuc...
Muscle fibers are multinucleated cells that arise during embryogenesis through the fusion of mononuc...
International audienceComplex animals build specialised muscles to match specific biomechanical and ...
International audienceComplex animals build specialised muscles to match specific biomechanical and ...
The flight muscle myofibril is a precisely assembled cytoskeletal network of contractileproteins tha...
Background: Higher animals generate an elaborate muscle-tendon network to perform their movements. T...
Background: Higher animals generate an elaborate muscle-tendon network to perform their movements. T...
Complex animals build specialised muscle to match specific biomechanical and energetic needs. Hence,...
AbstractFormation of the Drosophila larval body wall muscles requires the specification, coordinated...
Pattern formation in muscle development is often mediated by special cells called muscle organizers....
AbstractDuring insect myogenesis, myoblasts are organized into a pre-pattern by specialized organize...
Mitochondrial biogenesis and morphological changes are associated with tissue-specific functional de...
Myoblast fusion constitutes a fundamental aspect of muscle fiber growth, underlying the formation of...
Muscle development is a multistep process which includes myoblast diversification, proliferation, mi...
Muscle development is a multistep process which includes myoblast diversification, proliferation, mi...