Methyl 7-keto-1,2,3,4,4a,5,6,7-octahydronaphthoate (Va) has been prepared by the reduction of 7-methoxy-1,2,3,4-tetrahydronaphthoic acid (III) with lithium and ammonia followed by hydrolysis of the enol ether, esterification and migration of the double bond. Alkylation of Va has led to the substitution at the expected 8-position. Methyl 4-keto-7-methoxy-1,2,3,4-tetrahydronaphthoate (X), an intermediate in the preparation of III, has been converted into methyl 3-methyl-3-cyano-4-keto-7-methoxy-1,2,3,4-tetrahydronaphthoate (XIII)
The work described in this thesis is based on the synthesis and structural examination of several cy...
The development of a new synthesis of 2,6,7,7a-tetrahydro-lβ-hydroxy-4-formyl-7a-methylindene was un...
Two routes were evaluated for the preparation of multiply functionalized cyclohexane derivatives in ...
Michael condensation of 1-acetyl-3:4-dihydronaphthalene with ethyl sodio-acetoacetate leads to the f...
A new method for the preparation of the synthon (±)-2,6,7,7a-tetrahydro-1β-hydroxy-4-formyl-7aβ-meth...
A new method for the preparation of the synthon $(\pm)$-2,6,7,7a-tetrahydro-1$\beta$ -hydroxy-4-form...
A synthesis of 7-methyl-O:3:3-bicyclooctane-1-one-3-carboxylic acid has been described. By the oxida...
The synthesis and identification of 12 A-ring reduced 6 alpha-(and 6 beta-)hydroxylated compounds de...
A new strategy for the construction of A-ring aromatic steroids which resulted in the formal total s...
A synthesis of cyclopentanoporhydrophenanthrene derivative with the angular methyl groups in proper ...
Ozonization of 7-ketocholesteryl acetate has yielded methyl 5-keto-5, 7-seco-6-nor-3-cholestene-7-oa...
The first section of this thesis presents a review of the literature on hormones and anti-hormones, ...
The synthesis of 1-acetyl-6-oxo-8a-methyl-3,4,6,7,8,8a-hexahydronaphthalene, I is described
PART I. An attempted synthesis of tetrahydro-beta-vetivone, shown by St. Pfau and Plattner to be (B)...
3beta-Hydroxy-5alfa-cholest-7-ene-9alfa-carbonitrile was obtained via hydrocyanation of 3beta-acetox...
The work described in this thesis is based on the synthesis and structural examination of several cy...
The development of a new synthesis of 2,6,7,7a-tetrahydro-lβ-hydroxy-4-formyl-7a-methylindene was un...
Two routes were evaluated for the preparation of multiply functionalized cyclohexane derivatives in ...
Michael condensation of 1-acetyl-3:4-dihydronaphthalene with ethyl sodio-acetoacetate leads to the f...
A new method for the preparation of the synthon (±)-2,6,7,7a-tetrahydro-1β-hydroxy-4-formyl-7aβ-meth...
A new method for the preparation of the synthon $(\pm)$-2,6,7,7a-tetrahydro-1$\beta$ -hydroxy-4-form...
A synthesis of 7-methyl-O:3:3-bicyclooctane-1-one-3-carboxylic acid has been described. By the oxida...
The synthesis and identification of 12 A-ring reduced 6 alpha-(and 6 beta-)hydroxylated compounds de...
A new strategy for the construction of A-ring aromatic steroids which resulted in the formal total s...
A synthesis of cyclopentanoporhydrophenanthrene derivative with the angular methyl groups in proper ...
Ozonization of 7-ketocholesteryl acetate has yielded methyl 5-keto-5, 7-seco-6-nor-3-cholestene-7-oa...
The first section of this thesis presents a review of the literature on hormones and anti-hormones, ...
The synthesis of 1-acetyl-6-oxo-8a-methyl-3,4,6,7,8,8a-hexahydronaphthalene, I is described
PART I. An attempted synthesis of tetrahydro-beta-vetivone, shown by St. Pfau and Plattner to be (B)...
3beta-Hydroxy-5alfa-cholest-7-ene-9alfa-carbonitrile was obtained via hydrocyanation of 3beta-acetox...
The work described in this thesis is based on the synthesis and structural examination of several cy...
The development of a new synthesis of 2,6,7,7a-tetrahydro-lβ-hydroxy-4-formyl-7a-methylindene was un...
Two routes were evaluated for the preparation of multiply functionalized cyclohexane derivatives in ...