A simple and efficient methodology for the enantiospecific synthesis of B-seco-C-aromatic taxanes starting from monoterpene (R)-carvone is described. Coupling of 6,6-dimethylcarvone 5 with appropriate arylethyl bromides followed by oxidation generates the enones 7, 15, 25, which are transformed into the 20-nor-B-seco-C-aromatic taxane derivatives 11, 17 and B-seco-C-aromatic taxane derivative 29 via degradation of the isopropenyl group
The microbially derived cis-1,2-dihydrocatechol 2 has been converted, via reaction sequences includi...
In connection with efforts to develop an efficient total synthesis of the biologically active natura...
This thesis centres on the synthesis of taxol analogues via late-stage hydroxylation with P450 enzym...
A simple and efficient methodology for the enantiospecific synthesis of B-seco-C-aromatic taxanes st...
905-914A simple and efficient methodology for the enantiospecific synthesis of B-seco-C-aromatic ta...
An enantiospecific approach to functionalised C-aromatic-8,9-seco-taxanes starting from the readily ...
1430-1436Enantiospecific syntheses of B-seco-nortaxanes have been accomplished starting from the r...
A highly stereo-and enantio-selective methodology for the construction of the chiral functionalised ...
A highly stereo- and enantio-selective methodology for the construction of the chiral functionalised...
Enantiospecific synthesis of functionalised chiral C-ring derivatives of taxanes, starting from R-ca...
Two alternative approaches to the BC-ring system of taxanes, suitable for generating both enantiomer...
Starting from (R)-carvone, the synthesis of chiral, functionalised C-aromatic-B-seco-taxanes and an ...
Chemical synthesis of natural products is typically inspired by the structure and function of a targ...
Department of Organic Chemistry, Indian Institute of Science, Bangalore-560 012 Manuscript received...
Chemical synthesis of natural products is typically inspired by the structure and function of a targ...
The microbially derived cis-1,2-dihydrocatechol 2 has been converted, via reaction sequences includi...
In connection with efforts to develop an efficient total synthesis of the biologically active natura...
This thesis centres on the synthesis of taxol analogues via late-stage hydroxylation with P450 enzym...
A simple and efficient methodology for the enantiospecific synthesis of B-seco-C-aromatic taxanes st...
905-914A simple and efficient methodology for the enantiospecific synthesis of B-seco-C-aromatic ta...
An enantiospecific approach to functionalised C-aromatic-8,9-seco-taxanes starting from the readily ...
1430-1436Enantiospecific syntheses of B-seco-nortaxanes have been accomplished starting from the r...
A highly stereo-and enantio-selective methodology for the construction of the chiral functionalised ...
A highly stereo- and enantio-selective methodology for the construction of the chiral functionalised...
Enantiospecific synthesis of functionalised chiral C-ring derivatives of taxanes, starting from R-ca...
Two alternative approaches to the BC-ring system of taxanes, suitable for generating both enantiomer...
Starting from (R)-carvone, the synthesis of chiral, functionalised C-aromatic-B-seco-taxanes and an ...
Chemical synthesis of natural products is typically inspired by the structure and function of a targ...
Department of Organic Chemistry, Indian Institute of Science, Bangalore-560 012 Manuscript received...
Chemical synthesis of natural products is typically inspired by the structure and function of a targ...
The microbially derived cis-1,2-dihydrocatechol 2 has been converted, via reaction sequences includi...
In connection with efforts to develop an efficient total synthesis of the biologically active natura...
This thesis centres on the synthesis of taxol analogues via late-stage hydroxylation with P450 enzym...